Intraductal carcinoma of prostate (IDC-P): from obscure to significant.
Intraductal carcinoma of prostate (IDC-P): from obscure to significant.
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DOI：
10.3978/j.issn.1000-9604.2016.01.04
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发表时间：
2016-02
期刊：
影响因子：
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通讯作者：
N. Chen;Qiao Zhou
中科院分区：
文献类型：
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作者：
N. Chen;Qiao Zhou
前列腺导管内癌（IDC-P）的概念经过多年的发展，其临床病理意义已经得到了更清楚的认识。在其他解剖部位（如乳腺），形态上的导管内恶性病变代表了恶性过程的早期阶段，与之相反，IDC-P现在已被普遍认为是其侵袭性病变晚期扩散的预后不利表现。我们在此简要回顾IDC-P概念的演变，组织学诊断标准和鉴别诊断，临床意义，以及最近IDC-P的分子数据。
The concept of intraductal carcinoma of prostate (IDC-P) has evolved over the years and its clinicopathologic significance has come to be more clearly appreciated. In contrast to morphologically malignant intraductal lesions that represent earlier stages of the malignant process in other anatomic sites such as the breast, IDC-P has now been generally recognized as a prognostically unfavorable manifestation of later stage spreading of its invasive counterpart. We here briefly review the evolution of the IDC-P concept, the histological diagnostic criteria and differential diagnosis, the clinical significance, as well as recent molecular data of IDC-P.