Pentamethylphenyl (Ph*) and Related Derivatives as Useful Acyl Protecting Groups for Organic Synthesis: A Preliminary Study
Pentamethylphenyl (Ph*) and Related Derivatives as Useful Acyl Protecting Groups for Organic Synthesis: A Preliminary Study
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DOI：
10.1055/s-0040-1707289
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发表时间：
2020-09-22
期刊：
影响因子：
2
通讯作者：
Donohoe, Timothy J.
中科院分区：
文献类型：
--
作者：
Cheong, Choon Boon;Frost, James R.;Donohoe, Timothy J.
报道了Ph* 基序衍生的酰基保护基的研究。虽然最初的研究表明，各种官能团与释放Ph* 基团所需的Br-2介导的裂解条件不相容，但研究了涉及使用不同试剂或Ph* 本身（Ph*OH）修饰的策略来解决这个问题。
A study of acyl protecting groups derived from the Ph* motif is reported. While initial studies indicated that a variety of functional groups were not compatible with the Br-2-mediated cleavage conditions required to release the Ph* group, strategies involving the use of different reagents or a modification of Ph* itself (Ph*OH) were investigated to solve this problem.