The Immunogenicity of Fractional Intradermal Doses of the Inactivated Poliovirus Vaccine Is Associated With the Size of the Intradermal Fluid Bleb.

The Immunogenicity of Fractional Intradermal Doses of the Inactivated Poliovirus Vaccine Is Associated With the Size of the Intradermal Fluid Bleb.
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DOI:
10.1093/cid/cix381
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发表时间:
2017-09-01
期刊:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
影响因子:
--
通讯作者:
Clarke E
Clarke E
中科院分区:
其他
文献类型:
--
作者:
Bibby J;Saidu Y;Umesi A;Moneke-Anyanwoke N;Bashorun AO;Hydara MB;Adigweme I;Adetifa JU;Okoye M;Roberts E;Clemens R;Bandyopadhyay AS;Muhammad AK;Mulwa S;Royals M;Jarrahian C;Jeffries D;Kampmann B;Clarke E

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The immunogenicity of fractional (one-fifth, 0.1 mL) intradermal doses of the inactivated poliovirus vaccine (ID fIPV) is positively correlated with the size of the intradermal fluid bleb. Training of vaccinators for campaign and routine ID fIPV administration should focus on generating an 8- to 10-mm bleb with each injection. NCT01847872
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