Chemoselective cross-metathesis reaction. Application to the synthesis of the C1-C14 fragment of amphidinol 3

Chemoselective cross-metathesis reaction. Application to the synthesis of the C1-C14 fragment of amphidinol 3
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DOI:
10.1021/ol0157095
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发表时间:
2001-05-17
期刊:
影响因子:
5.2
通讯作者:
Cossy, J
Cossy, J
中科院分区:
化学1区
文献类型:
--
作者:
BouzBouz, S;Cossy, J

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[图表]描述了amphidinol 3的C1-C14片段的有效合成。该合成是基于化学选择性交叉复分解反应和对映选择性烯丙基钛化。
[GRAPHICS]An efficient synthesis of the C1-C14 fragment of amphidinol 3 is described. The synthesis is based on chemoselective cross-metathesis reactions and enantioselective allyltitanations.