Aphasia and handedness in relation to hemispheric side, age at injury and severity of cerebral lesion during childhood.
Aphasia and handedness in relation to hemispheric side, age at injury and severity of cerebral lesion during childhood.
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失语症和惯用手与半球侧、受伤年龄和儿童时期脑损伤的严重程度有关。
DOI：
10.1093/brain/108.3.677
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发表时间：
1985
期刊：
影响因子：
--
通讯作者：
G. Watters
中科院分区：
文献类型：
--
作者：
F. Vargha;A. O’Gorman;G. Watters
本研究探讨了偏瘫儿童大脑半球损伤侧、损伤年龄、损伤严重程度等变量对语言能力和手优势的影响。脑损伤的严重程度由CT扫描显示的结构异常程度来定义。听觉言语理解和物体命名测试被用作产出性和接受性语言技能的指示器。对左撇子清单上一系列问题的回答提供了一种衡量手优势的评级标准。结果表明，语言障碍是所有左脑损伤患者组的表现特征。然而，在5岁后获得的左半球损伤的情况下，损伤更为严重。此外，出生前和出生后早期的左脑病变都会导致强烈的左旋。结论：语言障碍和左手优势表现的关键变量不是病变的严重程度，而是损伤时的年龄和病变的半球。
The effects of the variables of hemispheric side of lesion, age at injury and severity of cerebral damage on language performance and hand dominance were investigated in groups of hemiparetic children. Severity of cerebral damage was defined by the degree of structural abnormality shown on computed tomography (CT) scans. Tests of auditory verbal comprehension and object naming were used as indicators of productive and receptive language skills. The responses to a series of questions on a handedness inventory provided a rated measure of hand dominance. The results indicated that language deficits characterize the performance of all patient groups with left cerebral injuries. Impairments are more profound, however, in the case of left hemisphere injuries acquired after the age of 5 years. In addition, prenatal and early postnatal left cerebral lesions consistently result in strong sinistrality. It is concluded that the crucial variable underlying the demonstration of language deficits and left hand dominance is not severity of lesion but age at injury and hemispheric side of lesion.