Leptospirosis: skin wounds and control strategies, Thailand, 1999.
Leptospirosis: skin wounds and control strategies, Thailand, 1999.
复制标题
DOI：
10.3201/eid0812.020180
复制
发表时间：
2002-12
影响因子：
11.8
通讯作者：
Ashford DA
中科院分区：
文献类型：
--
作者：
Phraisuwan P;Whitney EA;Tharmaphornpilas P;Guharat S;Thongkamsamut S;Aresagig S;Liangphongphanthu J;Junthima K;Sokampang A;Ashford DA
1999年9月在泰国参加清理池塘的工人中爆发钩端螺旋体病后，进行了血清学调查。在一个队列的104人从一个村庄谁参加了池塘清洁活动，43（41.3%）是血清阳性的免疫球蛋白M抗体对钩端螺旋体，表明最近感染。只有17（39.5%）的43个血清反应阳性的人报告了最近的发热性疾病，其余的血清反应阳性的人被认为是无症状的，这表明无症状的钩端螺旋体病感染可能是常见的地方性钩端螺旋体病。多因素Logistic回归分析显示，穿长裤或长裙是钩体感染的独立保护因素（OR调整= 0.217），而身上有两处以上伤口是钩体感染的独立保护因素（OR调整= 3.97）。在端螺旋体病流行的地区，应加强教育工作，鼓励使用防护衣物。此外，伤口管理和避免潜在的污染水时，皮肤伤口的存在应包括在健康教育计划。
After an outbreak of leptospirosis in workers who participated in cleaning a pond during September 1999 in Thailand, a serologic survey was conducted. Among a cohort of 104 persons from one village who participated in pond cleaning activity, 43 (41.3%) were seropositive for immunoglobulin M antibodies against Leptospira, indicating recent infection. Only 17 (39.5%) of 43 seropositive persons reported a recent febrile illness; the remaining seropositive persons were considered asymptomatic, suggesting that asymptomatic leptospirosis infection may be common where leptospirosis is endemic. Multivariable logistic regression indicated that wearing long pants or skirts was independently protective against leptospirosis infection (ORadjusted = 0.217), while the presence of more than two wounds on the body was independently associated with infection (ORadjusted = 3.97). Educational efforts should be enhanced in areas where leptospirosis is endemic to encourage the use of protective clothing. In addition wound management and avoidance of potentially contaminated water when skin wounds are present should be included in health education programs.