Development and nationwide application of an antibiotic knowledge scale
Development and nationwide application of an antibiotic knowledge scale
复制标题
抗生素知识量表的研制及全国应用
DOI：
10.1016/j.ypmed.2020.106262
复制
发表时间：
2020-12-01
影响因子：
5.1
通讯作者：
Yin, Xiaoxv
中科院分区：
文献类型：
--
作者：
Li, Dandan;Yang, Heping;Yin, Xiaoxv
公众对抗生素的误解可能会导致其不适当的使用。目前，没有抗生素知识评估工具来解决这个问题。本研究旨在编制和验证抗生素知识量表（AKS），并应用该量表评估中国公众抗生素知识。在2017年6月招募的1180人中设计并验证了最初的18项AKS。剔除冗余项目后，对量表的信度和效度进行检验。随后，在全国范围内进行了调查，并使用多阶段抽样招募了12，772人，并使用开发的AKS进行了调查。使用逻辑回归模型来确定与抗生素知识贫乏相关的因素。最终的AKS包括2个筛选项目和15个知识评价项目。Cronbach’s alpha、重测信度和分半信度分别为0.91、0.88和0.89。这些知识评价项目加载在四个不同的因素，解释了70.72%的受访者之间的累积方差。应用该量表对12，772名参与者进行抗生素知识调查，平均得分为7.25分，67%的参与者抗生素知识贫乏，与男性、农村、文化程度低、经济状况差、居住在西部、缺乏抗生素知识有关。AKS在识别抗生素知识缺乏的人群方面表现出令人满意的信度和效度。重要的是，大多数参与者对抗生素的知识不足。因此，有必要进行干预，重点是提高公众对抗生素的认识。
Misconceptions about antibiotics among the public can potentially lead to their inappropriate use. Currently, there is no antibiotic knowledge assessment tool to address this issue. This study aimed to develop and validate an antibiotic knowledge scale (AKS) and apply this scale to assess public knowledge about antibiotics in China. An initial 18-item AKS was designed and validated among 1180 people recruited in June 2017. After removing redundant items, the reliability and validity of the AKS were examined. Subsequently, a nationwide survey was conducted, and 12,772 people were recruited using multistage sampling and surveyed using the developed AKS. A logistic regression model was used to identify the factors associated with poor knowledge about antibiotics. The final AKS included two screening items and fifteen knowledge evaluation items. Cronbach's alpha, test-retest reliability, and split-half reliability were 0.91, 0.88, and 0.89, respectively. These knowledge evaluation items were loaded in four distinct factors that explained 70.72% of cumulative variance among respondents. Using the developed AKS to assess public knowledge about antibiotics among 12,772 participants, the mean score on the AKS was 7.25 and 67% of participants had poor antibiotic knowledge, which was associated with male gender, rural residence, lower educational level, poor economic status, living in western China, and lacking education on antibiotics. The AKS demonstrated satisfactory reliability and validity in identifying the population with poor antibiotic knowledge. Importantly, the majority of participants had inadequate knowledge about antibiotics. Thus, it is necessary to conduct interventions focusing on improving public knowledge about antibiotics.