GLUCONEOGENESIS FROM CECAL PROPIONATE IN THE HORSE
GLUCONEOGENESIS FROM CECAL PROPIONATE IN THE HORSE
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DOI：
10.1079/bjn19850010
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发表时间：
1985-01-01
影响因子：
3.6
通讯作者：
SIMMONS, HA
中科院分区：
文献类型：
--
作者：
FORD, EJH;SIMMONS, HA
在2匹装有盲肠和结肠插管的设得兰类型小马的盲肠中测量了丙酸的产量，这些小马以干草或干草和小麦麸为饲料。连续鞘内输注14C标记的丙酸钠，并从右腹结肠起始处的插管中获取样本。同时进行ui.v。用输注[2-~3H]葡萄糖的方法测定总葡萄糖进入。干草日粮提供177kJ/kg体重时，盲肠丙酸平均产生量为19.6 mg/h(17.2~21.2 mg/h)；干草加麸皮日粮提供187kL/kg体重时，盲肠丙酸平均产生量为34.0(28.9~38.3)mg/h。每公斤体重平均总糖产量(mg/h)1匹为104匹(范围100-110)，其余135匹(123-153)。饮食率不受饮食的影响。大约7%的总葡萄糖产量来自盲肠中产生的丙酸，这一比例不受饮食或单个动物的影响。
The production of propionate in the cecum of the horse has been measured in 2 Shetland-type ponies fitted with cecal and colonic cannulas and fed on hay or on hay and wheat bran. A continuous intracecal infusion of 14C-labelled sodium propionate was used and samples were obtained from a cannula at the origin of the right ventral colon. A simultaneous ui.v. infusion of [2-3H]glucose was used to measure total glucose entry. On a hay diet which provided 177 kJ/kg body-weight per d, mean cecal propionate production was 19.6 (range 17.2-21.2) mg/h per kg body-weight and on a hay and wheat bran diet, which provided 187 kl/kg body-weight per d, mean cecal propionate production was 34.0 (range 28.9-38.3) mg/h per kg body-wt. Mean total glucose production (mg/h per kg body-wt) in 1 pony was 104 (range 100-110) and in the other 135 (range 123-153). Rates were not influenced by diet. About 7% of total glucose production was derived from propionate produced in the cecum and this percentage was unaffected by diet or by individual animals.