Experimental transmission, pathogenicity and physical-chemical properties of infectious spleen and kidney necrosis virus (ISKNV)
Experimental transmission, pathogenicity and physical-chemical properties of infectious spleen and kidney necrosis virus (ISKNV)
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DOI：
10.1016/s0044-8486(01)00639-1
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发表时间：
2002-01-21
期刊：
影响因子：
4.5
通讯作者：
Chan, SM
中科院分区：
文献类型：
--
作者：
He, JG;Zeng, K;Chan, SM
通过在中国培养的第一个已知宿主物种鳜鱼（sininiperca chuatsi）和其他20种硬骨鱼的感染试验，研究了传染性脾肾坏死病毒（ISKNV）的致病性。鳜鱼和大口黑鲈（Micropterus salmoides）的脾脏和肾脏材料经腹腔感染后极易感染。ISKNV在草鱼（Ctenopharyngodon idella）中未引起死亡，但组织病理学研究显示它们可能通过沐浴和腹腔感染感染。浸渍或注射暴露的IS其他物种未见死亡、临床或组织病理学征象。实验感染研究表明，鳜鱼的ISKNV感染可以通过受污染的水从感染的鱼传染给健康的鱼。ISKN只发生在温度高于20℃的鳜鱼中。评估了病毒对消毒剂、高pH值和低pH值处理、紫外线照射以及在选定温度下储存的抗性。(C) 2002 Elsevier Science B.V.版权所有
The pathogenicity of infectious spleen and kidney necrosis virus (ISKNV) was examined by infection trials in the first known host species, the mandarinfish, Siniperca chuatsi, and in 20 other teleosts cultured in China. Mandarinfish and large-mouth bass, Micropterus salmoides, were highly susceptible to infection after intraperitoneal infection of ISKNV in spleen and kidney materials from infected fish. ISKNV did not induce mortality in grass carp (Ctenopharyngodon idella), but histopathological studies revealed that they might be infected by both bathing and intraperitoneal infection. No deaths, clinical or histopathological signs were found in the IS other species exposed by immersion or injection. Experimental infection studies showed that ISKNV infection in mandarinfish could be transmitted from infected to healthy fish through contaminated water. ISKN only occurred in mandarinfish cultured at temperature above 20degreesC. The resistance of the virus to treatment with disinfectants, high and low pH and UV irradiation, as well as storage at selected temperatures was assessed. (C) 2002 Elsevier Science B.V. All rights reserved.