Amino acid-mediated loading of Ag NPs and tannic acid onto cotton fabrics: increased antibacterial activity and decreased cytotoxicity
Amino acid-mediated loading of Ag NPs and tannic acid onto cotton fabrics: increased antibacterial activity and decreased cytotoxicity
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DOI：
10.1016/j.apsusc.2021.151821
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发表时间：
2021-11
影响因子：
6.7
通讯作者：
Yang Wu;Sheng Yang;Feiya Fu;Jingjing Zhang;Jianhua Li;Tingfang Ma;Xiangdong Liu;Juming Yao-
中科院分区：
文献类型：
--
作者：
Yang Wu;Sheng Yang;Feiya Fu;Jingjing Zhang;Jianhua Li;Tingfang Ma;Xiangdong Liu;Juming Yao-
本文首次将L-半胱氨酸（Cys）通过酯化反应键合到棉无纺布表面。在这种方式中，Ag+和单宁酸（TA）通过络合和氢键相互作用吸附到改性织物上。在可持续的一步氧化还原反应之后，制备了用Ag NPs和TA修饰的Cys改性的CO织物（CO-Cys-Ag-TA）。由于半胱氨酸和TA的稳定作用，合成的银纳米颗粒的平均尺寸为88.9 nm的均匀分布在改性织物表面。通过对比实验发现，载银纳米粒子负载TA后抗菌活性得到提高，载银纳米粒子的负载显著降低了TA的细胞毒性。在此背景下，CO-Cys-Ag-TA对S. aureusandE.大肠杆菌的去除率接近100%，经50次洗涤后，抗菌活性大于98.5%。当CO-Cys-Ag-TA浓度为0.1~0.8 mg/mL时，细胞活力可达88.0%。
In this paper, L-cysteine (Cys) is firstly bonded to the surface of cotton non-woven (CO) fabric as esterification. In this way, Ag+and tannic acid (TA) are adsorbed onto the modified fabric via complexation and hydrogen bond interaction. After a sustainable one-step redox reaction, a Cys modified CO fabric decorated with Ag NPs and TA (CO-Cys-Ag-TA) is prepared. Because of the stabilizing effect of Cys and TA, the synthesized Ag NPs with a mean size of 88.9 nm are uniformly distributed on the modified fabric surface. Through the comparative test, it has been revealed that the antibacterial activity of Ag NPs is improved after loading TA, and the loading of Ag NPs significantly reduces the cytotoxicity of TA. In this context, the bacteriostatic reduction rate of CO-Cys-Ag-TA againstS. aureusandE. coliis close to 100%, and its antibacterial activities are greater than 98.5% after 50 washing cycles. Meanwhile, its cell viability value reaches up to 88.0% with the presence of 0.1 mg/mL to 0.8 mg/mL CO-Cys-Ag-TA.