ScopeViewer: A Browser-Based Solution for Visualizing Spatial Transcriptomics Data.
ScopeViewer: A Browser-Based Solution for Visualizing Spatial Transcriptomics Data.
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ScopeViewer：基于浏览器的空间转录组数据可视化解决方案。
DOI：
10.1101/2023.07.24.549256
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发表时间：
2023
期刊：
影响因子：
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通讯作者：
Zhan,Xiaowei
中科院分区：
文献类型：
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作者：
Luo,Danni;Robertson,Sophie;Zhan,Yuanchun;Rong,Ruichen;Wang,Shidan;Jiang,Xi;Yang,Sen;Palmer,Suzette;Jia,Liwei;Li,Qiwei;Xiao,Guanghua;Zhan,Xiaowei
空间转录组学（ST）能够在特定的空间背景和组织形态中对分子特征进行高分辨率的询问。尽管它的潜力，ST数据的可视化是一项具有挑战性的任务，由于在处理，共享和可视化的大型图像数据集与molecular information.ResultsWe介绍ScopeViewer，一个基于浏览器的软件，旨在克服这些挑战的复杂性。ScopeViewer提供以下功能：（1）它以各种缩放级别可视化大图像数据和相关注释，允许对数据进行复杂的探索;（2）它支持原始图像沿着注释的双重交互式查看，提供对上下文的全面理解;（3）它以优化的带宽显示空间分子特征，确保流畅的用户体验;和（4）它通过规避数据传输来增强数据安全性。https://datacommons.swmed.edu/scopeviewer
MotivationSpatial transcriptomics (ST) enables a high-resolution interrogation of molecular characteristics within specific spatial contexts and tissue morphology. Despite its potential, visualization of ST data is a challenging task due to the complexities in handling, sharing and visualizing large image datasets together with molecular information.ResultsWe introduce ScopeViewer, a browser-based software designed to overcome these challenges. ScopeViewer offers the following functionalities: (1) It visualizes large image data and associated annotations at various zoom levels, allowing for intricate exploration of the data; (2) It enables dual interactive viewing of the original images along with their annotations, providing a comprehensive understanding of the context; (3) It displays spatial molecular features with optimized bandwidth, ensuring a smooth user experience; and (4) It bolsters data security by circumventing data transfers.AvailabilityScopeViewer is available at: https://datacommons.swmed.edu/scopeviewer