SYRINGOPEPTINS, NEW PHYTOTOXIC LIPODEPSIPEPTIDES OF PSEUDOMONAS-SYRINGAE PV SYRINGAE
SYRINGOPEPTINS, NEW PHYTOTOXIC LIPODEPSIPEPTIDES OF PSEUDOMONAS-SYRINGAE PV SYRINGAE
复制标题
DOI：
10.1016/0014-5793(91)81115-o
复制
发表时间：
1991-10-07
期刊：
影响因子：
3.5
通讯作者：
SIMMACO, M
中科院分区：
文献类型：
--
作者：
BALLIO, A;BARRA, D;SIMMACO, M
本文报道了植物病原菌Pseudomonasseringae pv.已确定的化学方法，H-1和C-13 NMR光谱和FAB质谱的组合。两种产生阿雷帕霉素的菌株得到3-羟基癸酰基-Dhb-Pro-Val-Val-Ala-Ala-Val-Val-Dhb-Ala-Val-Ala-Ala-Dhb-aThr -Ser-Ala-Dhb-Ala-Dab-Dab-Tyr，其中Tyr酰化aThr以形成大环内酯环，以及较少量的3-羟基十二烷酰基同系物。获得的证据是，第三种产雷帕霉素的菌株和产雷帕霉素毒素的菌株合成3-羟基癸酰基-Dhb-Pro-Val-Ala-Ala-Val-Leu-Ala-Ala-Dhb-Val-Dhb-Ala-Val-Ala-Ala-Dhb-aThr-Ser-Ala-Val-Ala-Dab-Dab-Tyr，其中Tyr和aThr再次形成大环内酯环，以及较少量的3-羟基十二烷酰基同系物。
The primary structure of some new lipodepsipeptides named syringopeptins, produced by plant pathogenic strains of Pseudomonas syringae pv. syringae has been determined by a combination of chemical methods, H-1 and C-13 NMR spectroscopy and FAB mass spectrometry. Two syringomycin-producing strains afforded 3-hydroxydecanoyl-Dhb-Pro-Val-Val-Ala-Ala-Val-Val-Dhb-Ala-Val-Ala-Ala-Dhb-aThr -Ser-Ala-Dhb-Ala-Dab-Dab-Tyr, with Tyr acylating aThr to form a macrolactone ring, and smaller amounts of the 3-hydroxydodecanoyl homologue. Evidence was obtained that a third syringomycin-producing strain and a syringotoxin-producing strain synthesize 3-hydroxydecanoyl-Dhb-Pro-Val-Ala-Ala-Val-Leu-Ala-Ala-Dhb-Val-Dhb-Ala-Val-Ala-Ala-Dhb-aThr-Ser-Ala-Val-Ala-Dab-Dab-Tyr, with Tyr and aThr forming again the macrolactone ring, and smaller amounts of the 3-hydroxydodecanoyl homologue.