Fluctuating Lipid Bilayer in an Arbitrary Potential: Theory and Experimental Determination of Bending Rigidity

Fluctuating Lipid Bilayer in an Arbitrary Potential: Theory and Experimental Determination of Bending Rigidity
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任意电位下波动的脂质双层:弯曲刚度的理论和实验测定

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发表时间:
2003
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通讯作者:
François Graner
François Graner
中科院分区:
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作者:
K. Mecke;T. Charitat;François Graner

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我们考虑在外部电势和有限温度下靠近基底的膜的位置波动。我们推导出平均膜位置及其均方根波动幅度的自洽方程,该方程在远低于非结合转变的中等波动范围内。这些自洽方程可以求解任意势。我们首先检查它们是否存在特殊的已知情况,然后将我们的方法应用于脂质双层,其中范德华吸引力通过与硬壁相关的水合排斥来平衡。最后,我们将这些结果与最近的脂质双层实验进行比较。 1
We consider the position fluctuations of a membrane close to a substrate in an external potential and at finite temperature. We derive self-consistent equations for the average membrane position and its root mean square fluctuation amplitude in the range of moderate fluctuations much below the unbinding transition. These self-consistent equations can be solved for arbitrary potentials. We first check them for special known cases, then we apply our approach to lipid bilayers where van der Waals attractions are balanced by hydration repulsion associated to a hard wall. Finally, we compare these results with recent experiments on lipid bilayer. 1