3-DIMENSIONAL STRUCTURE OF LUMINAL PLASMA-MEMBRANE PROTEIN FROM URINARY-BLADDER
3-DIMENSIONAL STRUCTURE OF LUMINAL PLASMA-MEMBRANE PROTEIN FROM URINARY-BLADDER
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DOI：
10.1016/s0022-2836(83)80048-5
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发表时间：
1983-01-01
影响因子：
5.6
通讯作者：
WADE, RH
中科院分区：
文献类型：
--
作者：
BRISSON, A;WADE, RH
本文研究了尿路上皮细胞膜蛋白的结构。在35埃下获得三维图。从负染色的膜蛋白二维阵列的分辨率。晶格空间群具有对称性p6 [6-fold]。在垂直于膜平面的投影上可分辨出不包括膜的区域（12）。在三维重建中，这些区域似乎被限制在膜的一侧，并形成延伸50埃的突起。从膜中出来。在膜的胞质侧没有观察到周期性结构，这表明该蛋白不是跨膜蛋白。
The structure of the membrane protein from urothelial plasma membrane was investigated. A 3-dimensional map was obtained at 35 .ANG. resolution from negatively stained 2-dimensional arrays of membrane proteins. The lattice space group has the symmetry p6 [6-fold]. Stain-excluding areas (12) are resolvable on projections perpendicular to the membrane plane. In the 3-dimensional reconstruction these areas appear to be restricted to 1 side of the membrane and form protrusions that extend 50 .ANG. out of the membrane. No periodic structure is observed at the cytoplasmic side of the membrane, which suggests that the protein is not a transmembrane protein.