Tackling contamination of the hospital environment by methicillin-resistant Staphylococcus aureus (MRSA):: a comparison between conventional terminal cleaning and hydrogen peroxide vapour decontamination
Tackling contamination of the hospital environment by methicillin-resistant Staphylococcus aureus (MRSA):: a comparison between conventional terminal cleaning and hydrogen peroxide vapour decontamination
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DOI：
10.1016/j.jhin.2004.03.006
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发表时间：
2004-05-01
影响因子：
6.9
通讯作者：
Parks, MJ
中科院分区：
文献类型：
--
作者：
French, GL;Otter, JA;Parks, MJ
医院环境有时可能窝藏耐甲氧西林金黄色葡萄球菌（MRSA），但通常不被视为MRSA感染的主要来源。我们在受MRSA感染的伦敦教学医院的外科病房进行了一项前瞻性研究，并比较了标准清洁与过氧化氢蒸汽去污新方法的有效性。MRSA污染，表面擦拭测量之前和之后进行了比较，符合英国国家标准，或过氧化氢蒸汽去污终端清洁。所有隔离室、病房和浴室都被MRSA污染，并确定了几种耐甲氧西林金黄色葡萄球菌。MRSA在可能将微生物转移到工作人员手中的场所很常见，并与非MRSA患者使用的区域和床架隔离。在清洁前采集的359个拭子中，74%产生了MRSA，70%通过直接平板接种。清洁后，所有区域仍然受到污染，124个拭子中有66%产生MRSA，74%通过直接平板接种。相比之下，在将6个房间暴露于过氧化氢蒸汽后，85个拭子中只有1个（1.2%）产生MRSA，仅通过富集培养。医院环境可能会被MRSA广泛污染，而标准清洁方法无法消除这种污染。相比之下，过氧化氢蒸汽消毒是从房间、家具和设备中根除MRSA的一种非常有效的方法。需要进一步的工作来确定MRSA环境污染的重要性以及有效去污对医院感染率的影响。(C)2004年医院感染学会。由爱思唯尔有限公司出版。保留所有权利。
The hospital environment can sometimes harbour methicillin-resistant Staphylococcus aureus (MRSA) but is not generally regarded as a major source of MRSA infection. We conducted a prospective study in surgical wards of a London teaching hospital affected by MRSA, and compared the effectiveness of standard cleaning with a new method of hydrogen peroxide vapour decontamination. MRSA contamination, measured by surface swabbing was compared before and after terminal cleaning that complied with UK national standards, or hydrogen peroxide vapour decontamination. All isolation rooms, ward bays and bathrooms tested were contaminated with MRSA and several antibiogram types were identified. MRSA was common in sites that might transfer organisms to the hands of staff and was isolated from areas and bed frames used by non-MRSA patients. Seventy-four percent of 359 swabs taken before cleaning yielded MRSA, 70% by direct plating. After cleaning, all areas remained contaminated, with 66% of 124 swabs yielding MRSA, 74% by direct plating. In contrast, after exposing six rooms to hydrogen peroxide vapour, only one of 85 (1.2%) swabs yielded MRSA, by enrichment culture only. The hospital environment can become extensively contaminated with MRSA that is not eliminated by standard cleaning methods. In contrast, hydrogen peroxide vapour decontamination is a highly effective method of eradicating MRSA from rooms, furniture and equipment. Further work is needed to determine the importance of environmental contamination with MRSA and the effect on hospital infection rates of effective decontamination. (C) 2004 The Hospital Infection Society. Published by Elsevier Ltd. All rights reserved.