Geographic distribution of human immunodeficiency virus markers in parenteral drug abusers.
Geographic distribution of human immunodeficiency virus markers in parenteral drug abusers.
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人类免疫缺陷病毒标记物在胃肠外药物滥用者中的地理分布。
DOI：
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发表时间：
1988
影响因子：
12.7
通讯作者：
J. Jaffe
中科院分区：
文献类型：
--
作者：
W. Lange;F. Snyder;D. Lozovsky;V. Kaistha;M. A. Kaczaniuk;J. Jaffe
美国六个地区的药物滥用治疗项目合作开展了一项旨在监测人类免疫缺陷病毒（HIV）抗体血清阳性率趋势的研究。面对吸毒行为的相似性，艾滋病毒血清阳性率的巨大差异对预防具有重要意义。在纽约市地区（哈莱姆、布鲁克林），1986年底获得的样本中有61%（N = 280）呈阳性，而1985年初的样本中有50%（N = 585）呈阳性。在马里兰州的巴尔的摩，代表11个项目的29%的样本（N = 184）呈阳性。相比之下，来自远离东北走廊的项目的样本的比率要低得多：科罗拉多的丹佛为5%（N = 100）;德克萨斯州的圣安东尼奥为2%（N = 106）;南加州为1.5%（N = 413）;佛罗里达的坦帕为0%（N = 102）。与预期相反，报告的终生共用针头经历没有相应的差异，从纽约的70%到圣安东尼奥的99%不等。HIV血清阳性仅与地理位置和种族有关;然而，由于在血清阳性率仍然相对较低的地区，注射药物滥用者共用针头，这些地区可能容易受到东北部同样灾难性传播的影响。存在着一个机会之窗，迅速、有力和积极的预防努力可以产生重大影响。
Drug abuse treatment programs in six regions of the United States collaborated in a study aimed at monitoring trends in the seroprevalence of human immunodeficiency virus (HIV) antibodies. The wide disparities in HIV seroprevalence in the face of similarities in drug using behavior have important implications for prevention. In the New York City area (Harlem, Brooklyn), 61 per cent of samples (N = 280) obtained in late 1986 were positive, up from 50 per cent of samples (N = 585) in early 1985. In Baltimore, Maryland, 29 per cent of samples (N = 184) representing 11 programs were positive. In contrast, samples from programs distant from the Northeast corridor had far lower rates: Denver, Colorado 5 per cent (N = 100); San Antonio, Texas 2 per cent (N = 106); Southern California, 1.5 per cent (N = 413); and Tampa, Florida, 0 per cent (N = 102). Contrary to expectations, there was no corresponding difference in reported lifetime needle sharing experiences, which ranged from 70 per cent in New York to 99 per cent in San Antonio. HIV seropositivity was associated only with geographic location and ethnicity; however, because needle sharing is practiced by parenteral drug abusers in areas where seroprevalence is still relatively low, these areas are potentially vulnerable to the same catastrophic spread seen in the Northeast. A window of opportunity exists where prompt, vigorous, and aggressive efforts at prevention could have major impact.
吸毒者获得性免疫缺陷综合症（艾滋病）的流行及其控制建议。
影响因子：
3.9
作者：
Marmor,M;DesJarlais,DC;Friedman,SR;Lyden,M;el-Sadr,W
通讯作者：
el-Sadr,W