Low- and high-tech approaches to control Plasmodium parasite transmission by anopheles mosquitoes.
Low- and high-tech approaches to control Plasmodium parasite transmission by anopheles mosquitoes.
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DOI：
10.1155/2011/891342
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发表时间：
2011
影响因子：
2.2
通讯作者：
Dimopoulos G
中科院分区：
文献类型：
--
作者：
Cirimotich CM;Clayton AM;Dimopoulos G
事实证明，目前的努力不足以阻止疟原虫寄生虫的传播，从而阻止疟疾通过按蚊传播。因此，迫切需要一种新的策略来抑制蚊子的疟原虫感染。在本文中，我们总结了疟疾控制的两种方法，一种是基于蚊子的天然微生物群落抑制寄生虫的低技术策略，另一种是利用蚊子的遗传修饰使其对感染具有抵抗力的高技术策略，并讨论了这两种方法的优缺点。
Current efforts have proven inadequate to stop the transmission of Plasmodium parasites, and hence the spread of malaria, by Anopheles mosquitoes. Therefore, a novel arsenal of strategies for inhibiting Plasmodium infection of mosquitoes is urgently needed. In this paper, we summarize research on two approaches to malaria control, a low-tech strategy based on parasite inhibition by the mosquito's natural microflora, and a high-tech strategy using genetic modification of mosquitoes that renders them resistant to infection and discuss advantages and disadvantages for both approaches.