An aspermia rat mutant (as/as) with spermatogenic failure at meiosis.
An aspermia rat mutant (as/as) with spermatogenic failure at meiosis.
复制标题
减数分裂时生精失败的无精子症大鼠突变体（as/as）。
DOI：
10.1292/jvms.54.745
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发表时间：
1992
期刊：
影响因子：
--
通讯作者：
T. Imamichi
中科院分区：
文献类型：
--
作者：
H. Ikadai;J. Noguchi;M. Yoshida;T. Imamichi
对一个新发现的无精症大鼠突变株进行了睾丸组织学和缺陷遗传方式的研究。突变体的平均睾丸重量约为表型正常雄性的三分之一。精子发生在减数分裂时中断。粗线期精母细胞数量明显减少。可见次级精母细胞和少量圆形精细胞，但未见细长的精细胞和精子。粗线期晚期精母细胞胞质内有大的嗜碱性包涵体。遗传分析显示该缺陷为常染色体隐性遗传。该基因座为无精症(AS)。
A newly identified aspermia rat mutant was investigated on testicular histology and mode of inheritance of the defect. Average testis weight of mutants was about one-third of that of phenotypically normal males. Spermatogenesis was interrupted at meiosis. Pachytene spermatocytes significantly decreased in number. Secondary spermatocytes and few round spermatids were seen, but no elongated spermatids and sperms were observed. A large basophilic inclusion-like body existed in the cytoplasm of late pachytene spermatocytes. Genetic analysis revealed an autosomal recessive transmission of the defect. Aspermia (As) was designated for the locus.
哺乳动物精子发生过程中的基因表达。
影响因子：
3.6
作者：
Stern,L;Gold,B;Hecht,NB
通讯作者：
Hecht,NB
基因定义的男性不育小鼠模型。
影响因子：
--
作者：
Chubb,C
通讯作者：
Chubb,C
小鼠精子发生的遗传控制。
影响因子：
--
作者：
Handel,MA
通讯作者：
Handel,MA