Randomized-controlled study of treating attention deficit hyperactivity disorder of preschool children with combined electro-acupuncture and behavior therapy
Randomized-controlled study of treating attention deficit hyperactivity disorder of preschool children with combined electro-acupuncture and behavior therapy
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DOI：
10.1016/j.ctim.2010.08.002
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发表时间：
2010-10-01
影响因子：
3.6
通讯作者：
Wang, Xiaotong
中科院分区：
文献类型：
--
作者：
Li, Shasha;Yu, Bo;Wang, Xiaotong
目的：目的：探讨电针结合行为疗法治疗学龄前注意缺陷多动障碍（ADHD）的疗效。方法：将180例符合DSM-IV诊断标准的ADHD患儿分为3种亚型：以注意缺失为主型（PI型，60例）、以多动冲动为主型（HI型，60例）和混合型（CT型，60例）。在每个亚型中，将患者随机分为实验组和对照组，实验组接受电针和行为治疗，对照组接受假电针和行为治疗。治疗12个疗程后，按照国家中医药委员会制定的标准，通过测量ADHD核心症状的变化来评价疗效随访12周，半年后评价复发率。（1）PI亚型中，实验组治疗有效11例，治疗好转12例，对照组显效5例，好转12例，HI亚型试验组显效10例，好转17例，对照组白色显效4例，好转14例;在CI亚型中，实验组显效12例，好转12例，对照组显效5例，好转12例，总体比较实验组疗效优于对照组（p < 0.05）。(2)结论：电针结合行为疗法治疗学龄前儿童ADHD，对改善ADHD症状有积极作用。不良事件对患者影响轻微。结论：该联合治疗方案是可行的，但多中心随机对照试验尚需进一步研究。(C)2010爱思唯尔有限公司保留所有权利。
Objective: To study the effectiveness of electro-acupuncture with behavior therapy on preschool children with attention deficit hyperactivity disorder (ADHD).Methods: 180 preschool children with ADHD diagnosed by DSM-IV were classified into three subtypes: predominantly inattentive subtype (PI subtype, 60 cases), predominantly hyperactive-impulsive subtype (HI subtype, 60 cases) and combined subtype (CT subtype, 60 cases). In each subtype, the patients were recruited randomly into experimental group, which received electro-acupuncture and behavior therapy; and control group, which received sham electro-acupuncture and behavior therapy. The treatment efficacy was evaluated by measuring the change in core symptoms of ADHD according to the standard enacted by the national traditional Chinese medicine committee after 12 courses of treatment (lasted 12 weeks) and relapse rate was evaluated after a half-year follow up.Results: (1) In PI subtype, 11 cases showed effectiveness with treatment and 12 cases showed improvement with treatment among experimental group, while five cases showed effectiveness and 12 cases showed improvement among control group; in HI subtype, 10 cases showed effectiveness and 17 cases showed improvement among experimental group, white four cases showed effectiveness and 14 cases showed improvement among control group; in CI subtype, 12 cases showed effectiveness and 12 cases showed improvement among experimental group, while five cases showed effectiveness and 12 cases showed improvement among control group; The overall comparison manifested that the efficacy of experimental group was better than that of control group (p < 0.05). (2) The core symptoms of experimental group were significantly decreased than that of control group at half-year follow up (p < 0.05).Conclusion: The treatment of ADHD in preschool children with electro-acupuncture combining behavior therapy has positive effect in reducing symptoms of ADHD. Adverse events are mild to patients. It is recommendable for this combined therapy, while multi-center RCT needs to be further studied. (C) 2010 Elsevier Ltd. All rights reserved.