STRATEGIES OF MIXED SUBSTRATE UTILIZATION IN MICROORGANISMS
STRATEGIES OF MIXED SUBSTRATE UTILIZATION IN MICROORGANISMS
复制标题
DOI：
10.1098/rstb.1982.0055
复制
发表时间：
1982-01-01
期刊：
影响因子：
--
通讯作者：
DIJKHUIZEN, L
中科院分区：
文献类型：
--
作者：
HARDER, W;DIJKHUIZEN, L
在自然和人造环境中，微生物常常在各种功能相似的底物中生长。这些混合底物的利用模式通常取决于它们的浓度。当底物浓度较高(不限制生长)时，通常会观察到顺序利用和二次生长，支持最高生长速度的底物优先从混合物中利用。当底物浓度限制生长时，混合物中存在的各种化合物的同时利用似乎是一般的反应。最近关于混合底物在间歇和连续培养中的利用的研究揭示了在微生物中管理各种底物利用的控制机制的策略。但也许更重要的是，这些研究表明，在营养有限的自然生态系统中，混合底物利用在微生物竞争中可能具有重要意义。
In natural and man-made environments microorganisms often grow in the presence of a diversity of functionally similar substrates. The pattern of utilization of these mixed substrates is generally dependent upon their concentration. When substrates are present in high (not growth-limiting) concentrations, sequential utilization and diauxic growth is often observed and the substrate that supports the highest growth rate is utilized preferentially from the mixture. When the substrate concentrations are growth-limiting, simultaneous utilization of the various compounds present in the mixture appears to be the general response. Recent studies on mixed substrate utilization in both batch and continuous cultures have thrown light on the strategies of the control mechanisms that, in microbes, govern the utilization of the various substrates. But perhaps more importantly these studies have indicated the possible significance of mixed substrate utilization in microbial competition in nutrient-limited natural ecosystems.