Mexican-American Dementia Nomogram: Development of a Dementia Risk Index for Mexican-American Older Adults.
Mexican-American Dementia Nomogram: Development of a Dementia Risk Index for Mexican-American Older Adults.
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DOI：
10.1111/jgs.14531
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发表时间：
2016-12
影响因子：
6.3
通讯作者：
Markides KS
中科院分区：
文献类型：
--
作者：
Downer B;Kumar A;Veeranki SP;Mehta HB;Raji M;Markides KS
有几个风险指数来预测痴呆症在非西班牙裔白色人群存在，但没有这样的措施已经开发了老年墨西哥裔美国人。这项研究的目的是创建一个风险指数（墨西哥裔美国人痴呆症诺模图[MADeN]），预测65岁及以上墨西哥裔美国人在10年内的痴呆症。回顾性队列研究和纵向分析。德克萨斯州、新墨西哥州、科罗拉多、亚利桑那州和加州的1,739名西班牙裔老年人流行病学研究人群（H-EPESE）的参与者。痴呆症被定义为在简易精神状态检查中每年下降3分或更多，并且无法进行1项或更多日常活动。候选风险因素包括人口统计学特征、社会参与度、自我报告的健康状况、完成日常活动的能力和体力活动。MADeN包括年龄，性别，教育，没有朋友可以依靠，不参加社区活动，糖尿病，感觉忧郁，疼痛，日常生活中的工具性活动受损，以及无法行走半英里。曲线下面积为0.74（95% CI=0.70-0.78），评分≥ 16分的敏感性为0.65（95% CI=0.59-0.72），特异性为0.70（95% CI=0.67-0.73）。MADeN能够以中等准确度预测墨西哥裔美国老年人的痴呆症。MADeN有可能被用来识别老年墨西哥裔美国人谁可能受益于干预措施，以减少痴呆症的风险，并教育这一人群有关痴呆症的危险因素。
Several risk indices to predict dementia in non-Hispanic White populations exist, but no such measure has been developed for older Mexican Americans. The purpose of this study was to create a risk index (Mexican American Dementia Nomogram [MADeN]) that predicts dementia over a 10-year period for Mexican Americans aged 65 and older. Retrospective cohort study with longitudinal analysis. Texas, New Mexico, Colorado, Arizona, and California 1,739 participants of the Hispanic Established Populations for the Epidemiologic Study of the Elderly (H-EPESE). Dementia was defined as a decline of 3 or more points per year on the Mini Mental Status Exam and inability to perform 1 or more daily activities. Candidate risk factors included demographic characteristics, measures of social engagement, self-reported health conditions, ability to complete daily activities, and physical activity. The MADeN included age, gender, education, not having friends to count on, not attending community events, diabetes, feeling the blues, pain, impairment in instrumental activities of daily living, and unable to walk a half-mile. The area under the curve was 0.74 (95% CI=0.70–0.78) and a score of 16 points or higher had a sensitivity of 0.65 (95% CI=0.59–0.72) and specificity of 0.70 (95% CI=0.67–0.73). The MADeN is able to predict dementia in a population of older Mexican American adults with moderate accuracy. The MADeN has the potential be used to identify older Mexican American adults who may benefit from interventions to reduce dementia risk and to educate this population about risk factors for dementia.