Development of 5-silylethynyl-1,3-dioxolan-4-one as a new prochiral template for asymmetric phase-transfer catalysis
Development of 5-silylethynyl-1,3-dioxolan-4-one as a new prochiral template for asymmetric phase-transfer catalysis
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DOI：
10.1039/c0cc02334e
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发表时间：
2010-01-01
影响因子：
4.9
通讯作者：
Maruoka, Keiji
中科院分区：
文献类型：
--
作者：
Hashimoto, Takuya;Fukumoto, Kazuhiro;Maruoka, Keiji
5-硅基-1，3-二氧戊环-4-酮的相转移催化不对称烷基化反应和Michael加成反应是一种合成高模数度的含炔基叔基α-烷基-α-羟基酸的方法。
Phase-transfer catalyzed asymmetric alkylation and Michael addition of 5-silylalkynyl-1,3-dioxolan-4-one were developed as a novel strategy to provide highly modular tertiary alpha-alkyla-alpha-hydroxy acids bearing an alkyne moiety.