Synthesis of urea-tethered neoglycoconjugates and pseudooligosaccharides in water
Synthesis of urea-tethered neoglycoconjugates and pseudooligosaccharides in water
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DOI：
10.1021/ja056253f
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发表时间：
2006-03-29
影响因子：
15
通讯作者：
Isobe, M
中科院分区：
文献类型：
--
作者：
Ichikawa, Y;Matsukawa, Y;Isobe, M
探索了一种在水介质中合成脲苷的新方法。发现Steyermark的吡喃葡萄糖基恶唑烷酮是用于将葡萄糖基部分锚定到胺和硫醇上的良好合成子。本方法成功地应用于建立了一条在水中合成脲连接的新糖缀合物和假寡糖的新路线。
A novel approach to the synthesis of urea glycosides in aqueous media has been explored. Steyermark's glucopyranosyl oxazolidinone was found to be a good synthon for anchoring glucosyl moieties onto amines and thiols. The present method was successfully applied to establish a new route for the synthesis of urea-tethered neoglycoconjugates and pseudooligosaccharides in water.