THE CALLOSAL SYSTEM OF THE SUPERIOR PARIETAL LOBULE IN THE MONKEY
THE CALLOSAL SYSTEM OF THE SUPERIOR PARIETAL LOBULE IN THE MONKEY
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DOI：
10.1002/cne.902370107
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发表时间：
1985-01-01
影响因子：
2.5
通讯作者：
SBRICCOLI, A
中科院分区：
文献类型：
--
作者：
CAMINITI, R;SBRICCOLI, A
使用基于小麦胚芽凝集素结合辣根过氧化物酶的顺行和逆行轴浆运输的解剖技术，在猕猴（Macaca nemestrina 和 M. fasciculis）中研究了顶上小叶（布罗德曼第 5 区）的胼胝体连接。从矢状切片中，获得了包含胼胝体投射神经元（胼胝体传出区）和/或胼胝体末端轴突（胼胝体末端区域）的皮质组织体积的二维扁平计算机重建。胼胝体区位于区域 5（包括辅助感觉区）、区域 6 的有限部分（即辅助运动区）、区域 7b（外侧裂背侧岸皮质）和区域 7a 的有限部分（颞上沟喙侧岸上 3 区皮质）。研究的所有皮质区域中的胼胝体神经元虽然存在区域差异，但主要集中在第 IIIb 层，但在第 VI 层和第 V 层中也非常多。它们在其他皮质层中很少见。在异位投射到区域 5 的皮质区域中，由于存在大的胼胝体区域，胼胝体神经元的切向分布是不连续的。这些在区域 5 中没有观察到，尽管这里胼胝体神经元的分布在切向皮层平面上有增有减。进出区域 5 的胼胝轴突穿过胼胝体后压部的中线。在顶叶上小叶，它们以放射状斑块或柱状终止，跨越 I-IV 层。这些不同宽度(200-2000μm)的柱由相似尺寸的间隙隔开，没有这样的端子。胼胝体神经元不仅存在于胼胝体末端柱内，而且存在于胼胝体末端柱之间。位于胼胝体末端柱内的胼胝体神经元在统计上显着地比位于胼胝体末端柱之间的胼胝体神经元数量更多。胼胝体传出区占区域 5 切向域的 71%，而胼胝体终末区仅占 49%。这种差异具有统计学意义。胼胝体末端的不连续柱状排列和区域 5 外侧部分胼胝体神经元的周期性分布定义了 2 个不规则形状的胼胝体连接的主要带，它们面向内侧并平行于主要的结构边界，即区域 2 和区域 5 之间的边界以及区域 5 和区域 7 之间的边界。
The callosal connections of the superior parietal lobule, area 5 of Brodmann, were studied in macaque monkeys (Macaca nemestrina and M. fascicularis) using anatomical techniques based on anterogrde and retrograde axoplasmic transport of wheat-germ-agglutinin-conjugated horseradish peroxidase. From sagittal sections, 2-dimensional flattened computer reconstructions of the volumes of cortical tissue containing callosal-projecting neurons (callosal efferent zone) and/or callosal terminal axons (callosal terminal territory) were obtained. Callosal zones were found in area 5, including the supplementary sensory area, in a limited part of area 6, i.e., in the supplementary motor area, in area 7b, in the cortex of the dorsal bank of the sylvian fissure and in a limited part of area 7a, in the cortex of the upper 3rd of the rostral bank of the superior temporal sulcus. Callosal neurons in all cortical areas studied, though with regional variations, predominated in layer IIIb, but were also very numerous in layers VI and V. They were rare in other cortical laminae. In the cortical regions projecting heterotopically to area 5, the tangenital distribution of callosal neurons was discontinuous because of the presence of large acallosal regions. These were not observed in area 5, although here the distribution of callosal neurons waxed and waned in the tangential cortical plane. Callosal axons to and/or from area 5 crossed the midline in the posterior, presplenial part of the corpus callosum. In the superior parietal lobule they terminated in radial patches or columns, spanning layers I-IV. These columns of various width (200-2000 .mu.m) were separated by gaps of similar size, free of such terminals. Callosal neurons were present not only within, but also between, the callosal terminal columns. Callosal neurons located within the callosal terminal columns were, in a statistically significant way, more numerous than those located between them. The callosal efferent zone occupied 71% of the tangential domain of area 5, whereas the callosal terminal territory occupied only 49% of it. This difference is statistically significant. The discontinuous columnar arrangement of callosal terminals and the periodic distribution of callosal neurons in the lateral part of area 5 defined 2 main bands of callosal connections of irregular shape which were oriented mediolaterally and ran parallel to the main architectonic borders, the border between areas 2 and 5, and that between 5 and 7.