Asymmetry of Neuronal Combinatorial Codes Arises from Minimizing Synaptic Weight Change
Asymmetry of Neuronal Combinatorial Codes Arises from Minimizing Synaptic Weight Change
复制标题
神经组合编码的不对称性源于最小化突触权重变化
DOI:
10.1162/neco_a_00854
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发表时间:
2016
影响因子:
2.9
通讯作者:
Mauro M.
中科院分区:
文献类型:
--
作者:
Leibold;Christian ;Monsalve-Mercado;Mauro M.
Synaptic change is a costly resource, particularly for brain structures that have a high demand of synaptic plasticity. For example, building memories of object positions requires efficient use of plasticity resources since objects can easily change their location in space and yet we can memorize object locations. But how should a neural circuit ideally be set up to integrate two input streams (object location and identity) in case the overall synaptic changes should be minimized during ongoing learning? This letter provides a theoretical framework on how the two input pathways should ideally be specified. Generally the model predicts that the information-rich pathway should be plastic and encoded sparsely, whereas the pathway conveying less information should be encoded densely and undergo learning only if a neuronal representation of a novel object has to be established. As an example, we consider hippocampal area CA1, which combines place and object information. The model thereby provides a normative account of hippocampal rate remapping, that is, modulations of place field activity by changes of local cues. It may as well be applicable to other brain areas (such as neocortical layer V) that learn combinatorial codes from multiple input streams.
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影响因子:
2
作者:
Sheeja Navakkode;Sreedharan Sajikumar;T. Sacktor;J. Frey
通讯作者:
Sheeja Navakkode;Sreedharan Sajikumar;T. Sacktor;J. Frey
影响因子:
4.3
作者:
Roudi Y;Treves A
通讯作者:
Treves A
影响因子:
4.3
作者:
van Rossum MC;Shippi M;Barrett AB
通讯作者:
Barrett AB
影响因子:
3
作者:
Deshmukh SS;Knierim JJ
通讯作者:
Knierim JJ
DOI:
10.1523/jneurosci.0946-13.2013
发表时间:
2013-05-29
期刊:
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子:
--
作者:
Neunuebel JP;Yoganarasimha D;Rao G;Knierim JJ
通讯作者:
Knierim JJ