Regional myocardial perfusion abnormalities on xenon-133 imaging in patients with angina pectoris and normal coronary arteries.
Regional myocardial perfusion abnormalities on xenon-133 imaging in patients with angina pectoris and normal coronary arteries.
复制标题
心绞痛和正常冠状动脉患者的氙 133 成像局部心肌灌注异常。
DOI：
10.1016/s0002-9149(77)80088-x
复制
发表时间：
1977
期刊：
影响因子：
--
通讯作者：
E. Riihimäki
中科院分区：
文献类型：
--
作者：
O. Korhola;M. Valle;M. Frick;M. Wiljasalo;E. Riihimäki
With use of semiselective xenon-133 injections and gamma camera recording, myocardial scintigrams were obtained in a series of 20 patients with angina pectoris, abnormal exercise electrocardiograms and normal coronary arteries. Ten patients (Group I) exhibited localized perfusion defects and the other 10 (Group II) a homogeneous uptake of the tracer. Group I was characterized by more past myocardial infarctions and, most significantly, by male preponderance (P<0.001). Computer analysis of regional xenon-133 washout curves revealed that every patient in Group I had a reduced flow rate in the area of the perfusion defect (P<0.001). A comparison of this group with 26 patients with similarly abnormal scintigrams but coronary arterial obstruction revealed that myocardial perfusion was 16 to 18 percent greater in the group with normal coronary arteries. In three patients of this group, myocardial perfusion rates were not augmented by atrial pacing in contrast to the response in patients with coronary arterial obstruction.The data demonstrated localized perfusion abnormalities in half of the patients with angina pectoris and normal coronary arteries and constitute evidence that a metabolic disorder is not the sole mechanism for ischemia in this syndrome.
