PROK2, HRNR, and FIG4 as potential genetic biomarkers of high bleeding propensity in East Asian patients with acute coronary syndrome using ticagrelor

PROK2, HRNR, and FIG4 as potential genetic biomarkers of high bleeding propensity in East Asian patients with acute coronary syndrome using ticagrelor
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DOI：
10.1002/phar.2736
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发表时间：
2022-10
期刊：
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy
影响因子：
--
通讯作者：
Q. Xiang;Zhe Wang;Guangyan Mu;Qiu-fen Xie;Zhiyan Liu;Shuang Zhou;Hanxu Zhang;Zi-ning Wang;Kun Hu;Hongtao Song;Dongdong Yuan;Q. Xia;Yan Huang;Yi-min Cui
Q. Xiang;Zhe Wang;Guangyan Mu;Qiu-fen Xie;Zhiyan Liu;Shuang Zhou;Hanxu Zhang;Zi-ning Wang;Kun Hu;Hongtao Song;Dongdong Yuan;Q. Xia;Yan Huang;Yi-min Cui
中科院分区：
其他
文献类型：
--
作者：
Q. Xiang;Zhe Wang;Guangyan Mu;Qiu-fen Xie;Zhiyan Liu;Shuang Zhou;Hanxu Zhang;Zi-ning Wang;Kun Hu;Hongtao Song;Dongdong Yuan;Q. Xia;Yan Huang;Yi-min Cui

文献摘要

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使用替格瑞洛治疗时，东亚人的出血风险高于欧洲人。本研究旨在探讨与使用替格瑞洛的东亚急性冠脉综合征（ACS）患者高出血倾向相关的遗传指标。
East Asians have a higher risk of bleeding than Europeans when treated with ticagrelor. This study aimed to explore genetic indicators related to the high bleeding propensity in East Asian patients with acute coronary syndrome (ACS) using ticagrelor.