Interhemispheric transfer time differences related to aging and gender
Interhemispheric transfer time differences related to aging and gender
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DOI：
10.1016/0028-3932(95)00157-3
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发表时间：
1996-07-01
期刊：
影响因子：
2.6
通讯作者：
Moes, P
中科院分区：
文献类型：
--
作者：
Jeeves, MA;Moes, P
对用于响应的手对侧的非结构化刺激（“交叉”响应）和用于响应的手同侧的刺激（“非交叉”响应）的简单反应时间的差异，或交叉-非交叉差异（CUD）被认为是半球间转移时间（IHTT）的可靠指标。使用 CUD 范式对无胼胝体患者以及胼胝体大小或功能已知差异的各种人群进行的研究表明，这种胼胝体差异反映在记录的 CUD 时间的差异中。最近的研究表明，老年人的胼胝体尺寸减小，尤其是前部区域。为了评估随年龄增长胼胝体转移效率的任何潜在变化，从老年人（60 岁以上）和年轻受试者（18-30 岁）获得了 CUD。与年轻受试者相比，老年受试者的 CUD 显着延长，其中老年女性贡献最大。年轻受试者没有发现显着的性别差异。此外，所有亚组都发现了整体右场反应时间优势的意外趋势，并且右手反应的计算 CUD 比左手反应更大。版权所有 (C) 1996 爱思唯尔科学有限公司
The difference in simple reaction times to unstructured stimuli contralateral to the hand used for response ('crossed' responses) and those stimuli ipsilateral to the hand used for response ('uncrossed' responses)-or crossed-uncrossed difference (CUD) is;assumed to be a reliable index of interhemispheric transfer time (IHTT). Studies using the CUD paradigm with acallosal patients as well as a variety of populations with known variations in callosal size or functioning have demonstrated that such callosal differences are reflected in differences in recorded CUD times. Recent studies have suggested that elderly individuals show a reduction in size of the corpus callosum, particularly in the anterior region. In order to assess any potential change in callosal transfer efficiency with aging, CUDs were obtained from elderly (60+ years) and younger subjects (18-30 years). The elderly subjects showed a significantly elongated CUD compared to younger subjects, with elderly females contributing the greatest increase. No significant gender differences were found for younger subjects. In addition, an unexpected trend for an overall right field reaction time advantage was found for all subgroups, accompanied by a larger calculated CUD for right hand responses than for left hand responses. Copyright (C) 1996 Elsevier Science Ltd.