Thrombin-induced platelet aggregation is mediated by a platelet plasma membrane-bound lectin.
Thrombin-induced platelet aggregation is mediated by a platelet plasma membrane-bound lectin.
复制标题
凝血酶诱导的血小板聚集是由血小板质膜结合的凝集素介导的。
作者：
T. Gartner;D. Williams;F. Minion;D. Phillips
Throbin-activated human platelets cause agglutination of trypsinized, formalinized bovine erythrocytes. This lectin activity of stimulated platelets was blocked by galactosamine, glucosamine, mannosamine, lysine, and arginine, but not by N-acetylated sugars, other neutral sugars, or other amino acids. Inhibitors of the thrombin-induced lectin activity also blocked thrombin-induced platelet aggregation. It appears that a membrane surface component that has lectin activity mediates platelet aggregation.
