Current-induced magnetic resonance phase imaging
Current-induced magnetic resonance phase imaging
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DOI：
10.1006/jmre.1998.1680
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发表时间：
1999-03-01
影响因子：
2.2
通讯作者：
Li, SJ
中科院分区：
文献类型：
--
作者：
Bodurka, J;Jesmanowicz, A;Li, SJ
电流引起的相变已通过快速磁共振成像（MRI）技术成像。我们测量了体模脉冲电流刺激引起的磁共振相图，并检测了其灵敏度。脉冲电流感应相位图证明了检测模拟神经元放电的质子磁共振信号相位变化的可行性。在目前的实验设置下，可以检测到 1.7 +/- 0.3 nT 的磁场强度变化。我们还计算了体素内部电流 I 产生的平行于 B-0 的磁通密度 B-T 的平均值，作为导线位置的函数。计算结果与我们的观察结果一致，即对于相同的实验设置，电流引起的相位变化可能随着体素内导线的位置而变化。我们从可能直接 MRI 检测神经元活动的角度讨论了我们的发现，(C) 1999 年学术出版社。
Electric current-induced phase alternations have been imaged by fast magnetic resonance image (MRI) technology. We measured the magnetic resonance phase images induced by pulsed current stimulation from a phantom and detected its sensitivity. The pulsed current-induced phase image demonstrated the feasibility to detect phase changes of the proton magnetic resonance signal that could mimic neuronal firing. At the present experimental setting, a magnetic field strength change of 1.7 +/- 0.3 nT can be detected. We also calculated the averaged value of the magnetic flux density B-T parallel to B-0 produced by electric current I inside the voxel as a function of the wire position. The results of the calculation were consistent with our observation that for the same experimental setting the current-induced phase change could vary with location of the wire inside the voxel. We discuss our findings in terms of possible direct MRI detection of neuronal activity, (C) 1999 Academic Press.