Prevalence of High Jugular Bulb across Different Stages of Adulthood in A Chinese Population
Prevalence of High Jugular Bulb across Different Stages of Adulthood in A Chinese Population
复制标题
中国人群不同成年阶段颈静脉球部高位患病率
DOI：
10.14336/ad.2020.0215
复制
发表时间：
2020-08-01
影响因子：
7.4
通讯作者：
Chen, Zhengnong
中科院分区：
文献类型：
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作者：
Wang, Jingjing;Feng, Yanmei;Chen, Zhengnong
已发现搏动性耳鸣、耳闷、眩晕、听力障碍和前庭功能障碍与高位颈静脉球有关。该区域的解剖变化也会影响手术计划和方法。因此，了解高位颈静脉球的详细解剖结构对于中耳和侧颅底手术至关重要。高位颈静脉球的患病率尚不确定，因为数据通常来自颞骨标本和医院的患者报告。因此，有必要进行基于社区的流行病学研究来了解高位颈静脉球解剖的意义。在这里，我们报告了一项横断面研究，使用 3.0 T 磁共振成像来表征高颈静脉球的患病率和颈静脉球大小。此外，我们研究了高位颈静脉球的患病率与年龄相关变化之间的关系。我们招募了来自上海地区两个社区的 4539 名常住居民（9078 耳），他们在 2007 年至 2011 年间接受了磁共振成像。我们根据年龄将参与者分为四个亚组：35-44 岁（中年早期）、45-54 岁（中年）、55-64 岁（中年晚期）和 65-75 岁（成年晚期）。我们发现中国人群中颈静脉球高位的总体患病率为 14.5%。右侧高位颈静脉球的患病率较高，尤其是女性（均 p < 0.001）。高位颈静脉球的发生率在中年早期组较高，并随着年龄的增长逐渐减少，但在成年晚期组中仍然存在（p = 0.039）。这些发现提供了有关中国人群中高位颈静脉球的患病率以及年龄组分布的有用信息，表明即使对于那些没有耳部疾病的人也应该考虑高位颈静脉球。这项工作为进一步研究颈静脉球变化与疾病症状之间的关系奠定了基础。
Pulsatile tinnitus, ear fullness, vertigo, hearing disorders, and vestibular dysfunction have been found to be related to high jugular bulb. Anatomical variation in this region also affects surgical planning and approaches. Therefore, knowledge on the detailed anatomy of the high jugular bulb is critical for middle ear and lateral skull base surgery. Prevalence of high jugular bulb is uncertain as data are usually derived from temporal bone specimens and patient reports from hospitals. Therefore, a community-based epidemiological study is necessary to understand the significance of high jugular bulb anatomy. Here, we report a cross-sectional study to characterize the prevalence of high jugular bulb and jugular bulb size using a 3.0 T magnetic resonance imaging. Furthermore, we studied the relationship between the prevalence of high jugular bulb and age-related changes. We enrolled 4539 permanent residents (9078 ears) from two communities in the Shanghai region who underwent magnetic resonance imaging between 2007 and 2011. We divided participants into four subgroups according to age: 35-44 (early middle age), 45-54 (middle age), 55-64 (late middle age), and 65-75 (late adulthood) years. We found that the overall prevalence of high jugular bulb was 14.5% in a Chinese population. There was a higher prevalence of high jugular bulb on the right side and especially in women (both p < 0.001). The occurrence of high jugular bulb was higher in the early middle age group and gradually decreased with age, but was still present in the late adulthood group (p = 0.039). These findings provide useful information on the prevalence of high jugular bulb in a Chinese population and the distribution in age groups, suggesting that high jugular bulb should be considered, even in those without ear disorders. This work serves as a foundation for further research on the relationship between jugular bulb changes and disease symptoms.