Insulators as mediators of intra- and inter-chromosomal interactions: a common evolutionary theme.
Insulators as mediators of intra- and inter-chromosomal interactions: a common evolutionary theme.
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DOI：
10.1186/jbiol165
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发表时间：
2009-08-27
影响因子：
--
通讯作者：
Corces VG
中科院分区：
文献类型：
--
作者：
Ong CT;Corces VG
绝缘子元件介导染色体内和染色体间的相互作用。绝缘子蛋白CCCTC结合因子（CTCF）对几种动物的绝缘子功能很重要，但BMC分子生物学的一份报告显示，秀丽隐杆线虫，酵母和植物缺乏CTCF。替代蛋白质在这些生物体中可能具有类似的功能。
Insulator elements mediate intra- and inter-chromosomal interactions. The insulator protein CCCTC-binding factor (CTCF) is important for insulator function in several animals but a report in BMC Molecular Biology shows that Caenorhabditis elegans, yeast and plants lack CTCF. Alternative proteins may have a similar function in these organisms.