The normal Q-T interval.
The normal Q-T interval.
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正常 Q-T 间期。
DOI：
10.1016/0002-8703(62)90059-5
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发表时间：
1962
影响因子：
4.8
通讯作者：
Max A. Woodbury
中科院分区：
文献类型：
--
作者：
E. Simonson;L. Cady;Max A. Woodbury
1.1. 在考虑体质和生理变量以及使用电子计算机的10项附加心电图项目的情况下，对649名20至59岁的健康男性和311名健康女性确定了Q-T和R-R区间之间的相关性。在调查的众多因素中，只有年龄对Q-T和R-R区间之间的关系贡献很小，但具有统计学意义。作为最佳拟合，得到对数和线性回归方程。在实际应用中，这两种回归方程的差异很小，所以我们选择简单的线性回归方程。与临床应用中最常用的Q-T和R-R区间关系的其他六种公式相比，对数CWS(1)和线性CWS(2)回归方程在Q-T与R-R区间宽散点的极值附近与9名受试者的实际值差异最小。根据百分位数分布和线性回归方程的预测，心率上限（97.5%）和下限（2.5%）在每分钟56至115之间的正常范围内具有极好的一致性。为了便于临床应用，在5个心率范围内给出了Q-T间期的正常界限，并且被认为比以前建议的更可靠。讨论了用心率预测Q-T区间的局限性。
1.1. The correlation between the Q-T and the R-R intervals was determined in 649 healthy men and 311 healthy women from 20 to 59 years of age, with consideration of constitutional and physiologic variables, and ten additional electrocardiographic items using an electronic computer.2.2. Of the numerous factors investigated, only age made a small, but statistically significant, contribution to the relationship between the Q-T and the R-R intervals.3.3. As best fit, logarithmic and linear regression equations were obtained. In actual application the difference between these two regression equations was so small that the simple linear regression equation is preferred.4.4. In comparison with six other formulas for the relationship between Q-T and R-R intervals, most commonly used in clinical application, the logarithmic CWS(1) and the linear CWS(2) regression equations gave the least discrepancies to the actual values in 9 subjects near the extremes of the wide scatter of Q-T versus R-R intervals.5.5. There was excellent agreement in the range of heart rate from 56 to 115 per minute between upper (97.5 per cent) and lower (2.5 per cent) normal limits determined from the percentile distribution and predicted from the linear regression equation.6.6. The normal limits of the Q-T interval are presented in five ranges of heart rate for convenient clinical application, and are believed to be more reliable than those previously suggested. The limitations of prediction of the Q-T interval from the heart rate are discussed.