INCREASED REPRODUCTIVE FITNESS OF ESCHERICHIA-COLI LAMBDA-LYSOGENS
INCREASED REPRODUCTIVE FITNESS OF ESCHERICHIA-COLI LAMBDA-LYSOGENS
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DOI：
10.1128/jvi.21.2.554-559.1977
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发表时间：
1977-01-01
影响因子：
5.4
通讯作者：
EDLIN, G
中科院分区：
文献类型：
--
作者：
LIN, L;BITNER, R;EDLIN, G
大肠杆菌。在葡萄糖限制型趋化因子的有氧生长过程中，溶原比非溶原繁殖得更快。如果环境改为厌氧生长，情况就会相反，溶原的繁殖速度就会比非溶原慢。基于四氮唑染料分析，.lambda的适应度增加。有氧生长过程中的溶原似乎是由于葡萄糖变得有限时持续的高代谢率造成的，但非溶原的代谢率下降。.lambda。Rex基因是溶原生长优势所必需的，因为缺乏Rex功能导致。lambda。与非溶原相比，溶原失去了繁殖优势。
E. coli .lambda. lysogens reproduce more rapidly than nonlysogens during aerobic growth in glucose-limited chemostats. If the environment is changed to anaerobic growth, the situation is reversed, and the lysogen reproduces more slowly than the nonlysogen. Based on a tetrazolium dye assay, the increased fitness of the .lambda. lysogen during aerobic growth seems to result from a continued high metabolic rate as glucose becomes limiting, but the metabolic rate of the nonlysogen declines. The .lambda. rex gene is required for the growth advantage of lysogens, since lack of rex function causes .lambda. lysogens to lose their reproductive advantage over nonlysogens.