Can reliable values of Young's modulus be deduced from Fisher's (1971) spinning lens measurements?
Can reliable values of Young's modulus be deduced from Fisher's (1971) spinning lens measurements?
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DOI：
10.1016/j.visres.2005.07.012
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发表时间：
2006-04-01
期刊：
影响因子：
1.8
通讯作者：
Judge, SJ
中科院分区：
文献类型：
--
作者：
Burd, HJ;Wilde, GS;Judge, SJ
当前教科书对老花眼成因的看法很大程度上取决于 R.F. 报告的一系列实验。 Fisher 大约三十年前提出，特别是根据绕光轴旋转切除镜片引起的变形推断出的镜片杨氏模量值（Fisher，1971）。我们研究了费舍尔用于解释测试的数学程序中固有假设对杨氏模量推断值的影响程度，并研究了几种替代解释方法。结果表明，费舍尔原始方法中固有的建模假设可能导致在确定皮层和核的杨氏模量时出现系统错误。费舍尔的结论是，皮质比细胞核更硬，尤其是在中年时期，这可能是与这些系统误差相关的人为因素。此外，我们探索的模型都无法解释费舍尔的主张，即去除胶囊对旋转透镜中引起的变形仅产生适度的影响。 (c) 2005 Elsevier Ltd. 保留所有权利。
The current textbook view of the causes of presbyopia rests very largely on a series of experiments reported by R.F. Fisher some three decades ago, and in particular on the values of lens Young's modulus inferred from the deformation caused by spinning excised lenses about their optical axis (Fisher, 1971) We studied the extent to which inferred values of Young's modulus are influenced by assumptions inherent in the mathematical procedures used by Fisher to interpret the test and we investigated several alternative interpretation methods. The results suggest that modelling assumptions inherent in Fisher's original method may have led to systematic errors in the determination of the Young's modulus of the cortex and nucleus. Fisher's conclusion that the cortex is stiffer than the nucleus, particularly in middle age, may be an artefact associated with these systematic errors. Moreover, none of the models we explored are able to account for Fisher's claim that the removal of the capsule has only a modest effect on the deformations induced in the spinning lens. (c) 2005 Elsevier Ltd. All rights reserved.