Use of medications with potential oral adverse drug reactions in community-dwelling elderly.
Use of medications with potential oral adverse drug reactions in community-dwelling elderly.
复制标题
社区老年人使用具有潜在口服药物不良反应的药物。
DOI：
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发表时间：
1993
期刊：
影响因子：
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通讯作者：
J. Beck
中科院分区：
文献类型：
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作者：
I. Lewis;J. Hanlon;M. Hobbins;J. Beck
研究了来自杜克老年人流行病学研究既定人群的4，163人中具有潜在口腔健康影响的药物使用的患病率和指标。药物分为7个潜在的口服药物不良反应（POADR）类别。80%的参与者至少服用了七类药物中的一种。56.1%的参与者服用了可能导致口干症的药物，51.7%的参与者止血异常，23.4%的参与者发生了软组织反应，11.0%的参与者发生了味觉变化，8.7%的参与者发生了宿主抵抗力改变，5.0%的参与者发生了牙龈过度生长，2.4%的参与者发生了运动障碍。种族分层分析显示，任何POADR的药物使用与两个种族的女性显著相关（p < 0.001）。在非黑人中，≥ 75岁与POADR使用率较高相关。在过去的六个月里看过牙医的黑人比那些没有看过牙医的黑人更有可能服用POADR药物。POADR药物使用与居住地无关。老年人经常服用可能影响口腔健康的药物。
Prevalence and indicators of medication use with potential oral health implications among 4,163 people from the Duke Established Populations for Epidemiologic Studies of the Elderly were studied. Medications were grouped into seven potential oral adverse drug reaction (POADR) categories. Eighty percent of participants were taking at least one medication from any of the seven categories. Drugs with the potential to cause xerostomia were taken by 56.1%, abnormal hemostasis by 51.7%, soft tissue reactions by 23.4%, taste changes by 11.0%, alteration in host resistance by 8.7%, gingival overgrowth by 5.0%, and movement disorders by 2.4% of participants. Race-stratified analyses revealed that medication use with any POADR was significantly associated (p < 0.001) with being female for both races. Among nonblacks, being > or = 75 years old was associated with higher POADR use. Blacks who had a dental visit in the previous six months were more likely to take medications with POADR than those who did not. POADR medication use was not related to place of residence. Elderly often take medications with potential oral health impact.
使用口腔干燥药物的老年受试者唾液流速的差异。
DOI：
10.1016/0030-4220(91)90187-h
发表时间：
1991
期刊：
Oral surgery, oral medicine, and oral pathology
影响因子：
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作者：
Persson,RE;Izutsu,KT;Treulove,EL;Persson,R
通讯作者：
Persson,R