Coordinated Feeding Behavior in Trichoplax, an Animal without Synapses.
Coordinated Feeding Behavior in Trichoplax, an Animal without Synapses.
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DOI：
10.1371/journal.pone.0136098
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发表时间：
2015
期刊：
影响因子：
3.7
通讯作者：
Reese TS
中科院分区：
文献类型：
--
作者：
Smith CL;Pivovarova N;Reese TS
Trichoplax是一种小型盘状海洋后生动物，通过纤毛滑动附着在基质上并运动。尽管只有六种细胞类型并且缺乏突触，但Trichoplax协调了一系列复杂的行为，最终在藻类的外部消化中达到高潮。我们将联合收割机活细胞成像与电子显微镜相结合，以显示这是如何实现的。当Trichoplax滑过一片藻类时，它的纤毛停止跳动，因此它停止移动。其中一种细胞类型的亚群，亲脂细胞，同时分泌颗粒，其内容物迅速溶解藻类。这种分泌物是精确靶向的，因为只有位于藻类附近的亲脂细胞才会释放颗粒。这种动物在摄入海藻后会停下来，然后继续滑行。滑动的全局控制与嗜脂细胞分泌的精确局部控制相协调，表明存在细胞通信和整合的机制。
Trichoplax is a small disk-shaped marine metazoan that adheres to substrates and locomotes by ciliary gliding. Despite having only six cell types and lacking synapses Trichoplax coordinates a complex sequence of behaviors culminating in external digestion of algae. We combine live cell imaging with electron microscopy to show how this is accomplished. When Trichoplax glides over a patch of algae, its cilia stop beating so it ceases moving. A subset of one of the cell types, lipophils, simultaneously secretes granules whose content rapidly lyses algae. This secretion is accurately targeted, as only lipophils located near algae release granules. The animal pauses while the algal content is ingested, and then resumes gliding. Global control of gliding is coordinated with precise local control of lipophil secretion suggesting the presence of mechanisms for cellular communication and integration.