Trait anxiety as an independent predictor of poor health-related quality of life and post-traumatic stress symptoms in rectal cancer.
Trait anxiety as an independent predictor of poor health-related quality of life and post-traumatic stress symptoms in rectal cancer.
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DOI：
10.1348/135910708x400462
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发表时间：
2009-11
影响因子：
7.9
通讯作者：
Trinkaus KM
中科院分区：
文献类型：
--
作者：
Ristvedt SL;Trinkaus KM
旨在确定特质焦虑对直肠癌幸存者样本中健康相关生活质量 (HRQoL) 和创伤后应激症状 (PTSS) 的影响。在一项纵向研究中，对 80 名被诊断患有直肠癌的患者在两个时间点进行了评估。在初始治疗后不久的时间 1，参与者完成了状态-特质焦虑量表以及气质和性格量表伤害避免量表，这些量表被合并为特质焦虑的综合测量。在时间 1 后 2-5 年的时间 2，使用癌症治疗功能评估-结直肠量表 (FACT-C) 评估参与者的 HRQoL，并使用修订后的事件影响量表 (IES-R) 评估参与者的 PTSS。尽管许多患者报告表现不佳，但 HRQoL 和 PTSS 平均而言总体良好。较高水平的特质焦虑预示着所有 FACT-C 和 IES-R 总量表和子量表测量的得分较低。更严重的大便失禁与 FACT 情绪健康分量表、FACT-结直肠癌量表和所有 IES-R 量表的较差分数相关。男性比女性更有可能在 FACT 社会幸福感量表上得分较差，而那些远离积极治疗的患者在 FACT-结直肠癌量表上得分更高。结肠造口术的存在不会影响 HRQoL 或 PTSS。直肠癌诊断和治疗后数年，特质焦虑对 HRQoL 和 PTSS 产生显着影响。
To determine the influence of trait anxiety on patient reports of health-related quality of life (HRQoL) and post-traumatic stress symptoms (PTSS) in a sample of rectal cancer survivors. Eighty patients who had been diagnosed with rectal cancer were assessed at two points in time in a longitudinal study. At Time 1, soon after initial treatment, participants completed the State-Trait Anxiety Inventory and the Temperament and Character Inventory Harm Avoidance scale, which were combined into a composite measure of trait anxiety. At Time 2, 2-5 years following Time 1, participants were assessed for HRQoL using the Functional Assessment of Cancer Therapy-Colorectal scale (FACT-C) and for PTSS using the Impact of Event Scale-Revised (IES-R). HRQoL and PTSS were generally favourable on average, although many of the patients reported faring poorly. Higher levels of trait anxiety were predictive of poorer scores on all of the FACT-C and the IES-R total and subscale measures. More severe faecal incontinence was associated with poorer scores on the FACT Emotional well-being subscale, the FACT-Colorectal Cancer Scale, and all of the IES-R scales. Males were more likely than females to have poorer scores on the FACT Social well-being subscale, and those patients who were further out from active treatment had more favourable scores on the FACT-Colorectal Cancer Scale. The presence of a colostomy did not impact HRQoL or PTSS. Trait anxiety had a significant influence on HRQoL and PTSS several years following diagnosis and treatment of rectal cancer.