Diseases of poverty with high mortality in infants and children - Malaria, measles, lower respiratory infections, and diarrheal illnesses
Diseases of poverty with high mortality in infants and children - Malaria, measles, lower respiratory infections, and diarrheal illnesses
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DOI：
10.1196/annals.1425.035
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发表时间：
2008-01-01
期刊：
影响因子：
--
通讯作者：
Kaler, Stephen G.
中科院分区：
文献类型：
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作者：
Kaler, Stephen G.
疟疾、麻疹、下呼吸道感染和腹泻是常见的儿科疾病，在极端贫困的情况下往往是致命的。然而，在非贫困环境中，这些感染是以最小化死亡率的方式控制和管理的。从科学的角度来看，微生物之间的遗传变异是其流行病学，病理生理学，治疗和预防的常见和重要组成部分。从公共卫生的角度来看，相对简单的措施可以减少这些疾病的致命影响，直到成功的疫苗成为可用和免疫接种计划建立。在营养不良和其他贫困情况下，婴儿和儿童特别容易因感染而产生不良后果。
Malaria, measles, lower respiratory infections, and diarrheal illnesses are common pediatric medical problems that are often fatal in the context of extreme poverty. In nonpoor environments, however, these infections are controlled and managed in ways that minimize mortality. From a scientific perspective, genetic variation among microbes is a frequent and important component of their epidemiology, pathophysiology, treatment, and prevention. From a public health perspective, relatively simple measures can reduce the mortal effects of these diseases until successful vaccines become available and immunizations programs are established. Infants and children are especially vulnerable to poor outcomes from infections when undernutrition and other circumstances of poverty are present.