Opportunistic filamentous mycoses: aspergillosis, mucormycosis, phaeohyphomycosis and hyalohyphomycosis
Opportunistic filamentous mycoses: aspergillosis, mucormycosis, phaeohyphomycosis and hyalohyphomycosis
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DOI：
10.1111/j.1610-0387.2012.07994.x
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发表时间：
2012-09-01
影响因子：
3.6
通讯作者：
Bonifaz, Alexandro
中科院分区：
文献类型：
--
作者：
Maria Perusquia-Ortiz, Ana;Vazquez-Gonzalez, Denisse;Bonifaz, Alexandro
寄生性丝状真菌病广泛分布于世界各地。它们在欧洲很少见，但在发展中国家很常见。最常见的是曲霉菌（由于曲霉属）。主要表现为中性粒细胞减少症和免疫抑制;毛霉菌病，其特征在于糖尿病酮症酸中毒患者中的快速进展;由色素性真菌引起的暗色丝孢菌病，其引起轻度浅表或非常严重的深部疾病;以及由透明丝状真菌（镰刀菌属，假阿氏菌属，帚霉属（Scopulariopsis spp.）皮肤表现通常是继发于肺部或内脏疾病的传播，原发病例较少，由于直接接种到skin.We审查流行病学，临床，诊断和治疗的四个最重要的机会性丝状真菌病的数据：曲霉菌病，毛霉菌病，暗色丝孢真菌病和透明丝孢真菌病。
Opportunistic filamentous mycoses are widely distributed all over the world. They are rarely observed in Europe but are common in developing countries. The most common are the aspergilloses (due to Aspergillus spp.) mostly in neutropenia and immunosuppression; the mucormycoses characterized by rapid progression in patients with diabetic ketoacidosis; the phaeohyphomycoses due to pigmented fungi causing either a mild superficial or a very serious deep disease and the hyalohyphomycoses due to hyaline filamentous fungi (Fusarium spp., Pseudallescheria spp., Scopulariopsis spp.). Cutaneous manifestations are usually secondary to dissemination from pulmonary or visceral disease; primary cases are less frequent and due to direct inoculation into the skin.We review epidemiological, clinical, diagnostic, and therapeutic data on the four most important opportunistic filamentous mycoses: aspergillosis, mucormycosis, phaeohyphomycosis and hyalohyphomycosis.