A Surface Coating that Rapidly Inactivates SARS-CoV-2
A Surface Coating that Rapidly Inactivates SARS-CoV-2
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DOI：
10.1021/acsami.0c11425
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发表时间：
2020-08-05
影响因子：
9.5
通讯作者：
Ducker, William A.
中科院分区：
文献类型：
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作者：
Behzadinasab, Saeed;Chin, Alex;Ducker, William A.
导致新冠肺炎疾病的SARS-CoV-2病毒在固体中可以存活长达一周，因此人类感染的一个潜在途径是通过接触固体中的传染性剂量。我们已经制造并测试了一种涂层，该涂层旨在减少SARS-CoV-2在固体上的寿命。该涂层由氧化亚铜(Cu2O)颗粒与聚氨酯结合而成。在镀膜玻璃或不锈钢上放置1h后，病毒滴度比未涂膜的样品平均降低99.9%。以聚氨酯为基础的涂料的一个优点是，聚氨酯已经被用来涂覆大量的日常物品。我们的涂层可以很好地附着在玻璃和不锈钢以及人们在疫情期间可能不敢触摸的日常用品上，例如门把手、钢笔和信用卡键盘按钮。该涂层在交叉孵化耐久性测试中表现良好，在浸入水中13天或暴露在病毒和消毒的多次循环后仍保持完好和活性。
SARS-CoV-2, the virus that causes the disease COVID-19, remains viable on solids for periods of up to 1 week, so one potential route for human infection is via exposure to an infectious dose from a solid. We have fabricated and tested a coating that is designed to reduce the longevity of SARS-CoV-2 on solids. The coating consists of cuprous oxide (Cu2O) particles bound with polyurethane. After 1 h on coated glass or stainless steel, the viral titer was reduced by about 99.9% on average compared to the uncoated sample. An advantage of a polyurethane-based coating is that polyurethane is already used to coat a large number of everyday objects. Our coating adheres well to glass and stainless steel as well as everyday items that people may fear to touch during a pandemic, such as a doorknob, a pen, and a credit card keypad button. The coating performs well in the cross-hatch durability test and remains intact and active after 13 days of being immersed in water or after exposure to multiple cycles of exposure to the virus and disinfection.