A prospective study of stressful life events and schizophrenic relapse.
A prospective study of stressful life events and schizophrenic relapse.
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关于压力生活事件和精神分裂症复发的前瞻性研究。
DOI：
10.1037//0021-843x.98.4.407
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发表时间：
1989
影响因子：
4.6
通讯作者：
Hardesty,JP
中科院分区：
文献类型：
--
作者：
Ventura,J;Nuechterlein,KH;Lukoff,D;Hardesty,JP
在这项前瞻性纵向研究中，每月对 11 名在标准化维持药物治疗期间符合精神病复发或精神病显着恶化标准的 11 名新近发病的精神分裂症门诊患者以及 19 名在此随访期间未复发的患者进行有关生活事件的访谈。正如假设的那样，对于复发患者来说，在复发前一个月发生的独立生活事件（那些不是症状或个人影响的结果）的数量显着增加。这种增加相对于同一患者“非复发”期的类似月份或非复发患者1年标准化用药期间每月独立事件的平均数而言是明显的。这种设计的方法论进步以及这些发现与之前回顾性研究的一致性支持了这样的假设：生活事件有时可能“触发”精神分裂症发作。（PsycInfo 数据库记录 (c) 2022 APA，保留所有权利）
In this prospective, longitudinal study, 11 recent-onset schizophrenic outpatients who met criteria for psychotic relapse or significant psychotic exacerbation during a 1-year period of standardized maintenance medication, and 19 patients who did not relapse during this follow-up period, were interviewed monthly regarding life events. As hypothesized, for relapsing patients, a significantly higher number of independent life events (those not the result of symptomatology or personal influence) occurred in the month preceding relapse. This increase was apparent relative to either the analogous month of a" nonrelapse" period in the same patient or the average number of independent events per month during a 1-year standardized medication period for nonrelapsing patients. The methodological advances of this design as well as the consistency of these findings with those of previous retrospective studies supports the hypothesis that life events may sometimes" trigger" schizophrenic episodes.(PsycInfo Database Record (c) 2022 APA, all rights reserved)