Vertebrate endoderm development and organ formation.
Vertebrate endoderm development and organ formation.
复制标题
DOI:
10.1146/annurev.cellbio.042308.113344
复制
发表时间:
2009
影响因子:
11.3
通讯作者:
Wells JM
中科院分区:
文献类型:
--
作者:
Zorn AM;Wells JM
The endoderm germ layer contributes to the respiratory and gastrointestinal tracts, and all of their associated organs. Over the past decade, studies in vertebrate model organisms; including frog, fish, chick, and mouse; have greatly enhanced our understanding of the molecular basis of endoderm organ development. We review this progress with a focus on early stages of endoderm organogenesis including endoderm formation, gut tube morphogenesis and patterning, and organ specification. Lastly, we discuss how developmental mechanisms that regulate endoderm organogenesis are used to direct differentiation of embryonic stem cells into specific adult cell types, which function to alleviate disease symptoms in animal models.
登录
查看更多内容
影响因子:
11.8
作者:
Chung, Won-Suk;Shin, Chong Hyun;Stainier, Didier Y. R.
通讯作者:
Stainier, Didier Y. R.
影响因子:
11.8
作者:
Bjornson, CRR;Griffin, KJR;Kimelman, D
通讯作者:
Kimelman, D
DOI:
10.1073/pnas.0401654101
发表时间:
2004-05-18
影响因子:
11.1
作者:
Chawengsaksophak, K;de Graaff, W;Beck, F
通讯作者:
Beck, F
影响因子:
3.7
作者:
Bayha E;Jørgensen MC;Serup P;Grapin-Botton A
通讯作者:
Grapin-Botton A
影响因子:
2.7
作者:
Cervantes S;Yamaguchi TP;Hebrok M
通讯作者:
Hebrok M