Highly enantioselective quinoline synthesis via ene-type cyclization of 1,7-enynes catalyzed by a cationic BINAP-palladium(II) complex
Highly enantioselective quinoline synthesis via ene-type cyclization of 1,7-enynes catalyzed by a cationic BINAP-palladium(II) complex
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DOI：
10.1021/ja0292748
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发表时间：
2003-04-23
影响因子：
15
通讯作者：
Mikami, K
中科院分区：
文献类型：
--
作者：
Hatano, M;Mikami, K
首次在阳离子二氮杂多−钯(II)配合物催化下合成了六元环喹啉，得到了具有季碳中心或螺环的喹啉产物，其定量产率和~gt；99%ee。
The first highly enantioselective synthesis of a six-membered ring quinoline catalyzed by a cationic BINAP−palladium(II) complex is shown to afford the quinoline products having a quaternary carbon center or a spiro-ring in quantitative yield and >99% ee.