Prevalence of Negative Symptoms in Outpatients With Schizophrenia Spectrum Disorders Treated With Antipsychotics in Routine Clinical Practice: Findings From the CLAMORS Study

Prevalence of Negative Symptoms in Outpatients With Schizophrenia Spectrum Disorders Treated With Antipsychotics in Routine Clinical Practice: Findings From the CLAMORS Study
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DOI:
10.4088/jcp.08m04250yel
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发表时间:
2010-03-01
影响因子:
5.3
通讯作者:
Rejas, Javier
Rejas, Javier
中科院分区:
医学2区
文献类型:
--
作者:
Bobes, Julio;Arango, Celso;Rejas, Javier

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目的:分析门诊精神分裂症谱系障碍抗精神病药物治疗患者阴性症状的患病率。方法:2004年5月至2005年4月,对1,704例符合DSM-IV精神分裂症、精神分裂样障碍或情感障碍诊断标准的成人精神科门诊患者进行了横断面、回顾性、多中心研究。我们使用阳性和阴性综合征量表(PAN SS)阴性症状子量表的5个项目,当项目评分>3时,单独确定阴性症状的存在。当患者满足以下所有条件时,认为存在原发性阴性症状:相应项目得分>3分;
Objective: To analyze the prevalence of negative symptoms in antipsychotic-treated outpatients with schizophrenia spectrum disorders.Method: A cross-sectional, retrospective multicenter study was carried out between May 2004 and April 2005 in 1,704 adult psychiatric outpatients meeting DSM-IV criteria for schizophrenia, schizophreniform, or schizo-affective disorder. We used 5 items of the Positive and Negative Syndrome Scale (PAN SS) negative symptoms subscale to individually determine the presence of a negative symptom when the score on the item was >3. Primary negative symptoms were considered present when patients fulfilled all of the following: >3 score on the corresponding item;