A COMPETITIVE-EXCLUSION PRINCIPLE FOR PATHOGEN VIRULENCE
A COMPETITIVE-EXCLUSION PRINCIPLE FOR PATHOGEN VIRULENCE
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DOI：
10.1007/bf00276102
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发表时间：
1989-01-01
影响因子：
1.9
通讯作者：
THIEME, HR
中科院分区：
文献类型：
--
作者：
BREMERMANN, HJ;THIEME, HR
对于一个修改后的安德森和五月模型的主机寄生虫的动力学，它表明，不同水平的毒力的感染逐渐死亡，除了那些优化的基本繁殖率的致病寄生虫。在感染一种寄生虫菌株排除了其他菌株的额外感染的假设下，该结果成立。从技术上讲，该模型包括宿主的环境承载能力。一个阈值条件的推导，决定是否寄生虫坚持在主机人口。
For a modified Anderson and May model of host parasite dynamics it is shown that infections of different levels of virulence die out asymptotically except those that optimize the basic reproductive rate of the causative parasite. The result holds under the assumption that infection with one strain of parasite precludes additional infections with other strains. Technically, the model includes an environmental carrying capacity for the host. A threshold condition is derived which decides whether or not the parasites persist in the host population.