Postoperative radiotherapy for locally advanced colon cancer

Postoperative radiotherapy for locally advanced colon cancer
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DOI:
10.1007/bf02305760
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发表时间:
1996-09-01
影响因子:
3.7
通讯作者:
Amos, WR
Amos, WR
中科院分区:
医学2区
文献类型:
--
作者:
Amos, EH;Mendenhall, WM;Amos, WR

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背景资料:局部晚期结肠癌术后辅助放疗的作用是没有很好的documented.Methods:78例患者进行了B2-C结肠癌的完全切除术后接受放疗。28例患者接受小于或等于45戈伊; 50例患者接受50-55戈伊。27例患者接受以氟尿嘧啶为基础的辅助化疗,所有患者均随访至少3年,无患者失访。术后放疗50-55戈伊的5年局部控制率为96%,
Background: The role of adjuvant postoperative radiotherapy for locally advanced colon cancer is not well documented.Methods: Seventy-eight patients who underwent a complete resection of B2-C colon cancer received postoperative radiotherapy. Twenty-eight patients received less than or equal to 45 Gy; 50 patients received 50-55 Gy. Twenty-seven patients received adjuvant fluorouracil-based chemotherapy, All patients were followed for a minimum of 3 years; no patients were lost to follow-up.Results: The overall local control rate was 88%. The 5-year actuarial rate of local control was 96% after 50-55 Gy postoperative radiotherapy compared with 76% after