In humans Ib facilitation depends on locomotion while suppression of Ib inhibition requires loading
In humans Ib facilitation depends on locomotion while suppression of Ib inhibition requires loading
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DOI：
10.1016/j.brainres.2005.12.069
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发表时间：
2006-03-03
期刊：
影响因子：
2.9
通讯作者：
Duysens, J
中科院分区：
文献类型：
--
作者：
Faist, M;Hoefer, C;Duysens, J
力反馈在步态中的作用仍然是一个有争议的问题。从对猫的研究可知，来自小腿三头肌的高尔基腱器官的输入在运动过程中确实产生lb易化，而不是自生抑制。在人类中，Stephens和Yang（Stephens，MJ.，杨，J.F.，1996.短潜伏期，非互惠组I抑制在人类行走的站立阶段减少。Brain Res.743，24-31）发现自主收缩导致Ib抑制的减少。在步态过程中，他们甚至观察到一部分受试者的lb易化。这就提出了一个问题，即这些变化的关键因素是腿部的负荷还是运动。为了研究这个问题，研究了在坐着、仰卧、仰卧时足底施加300 N压力、站立和称为“减少”步态的有节奏的加载和卸载任务期间的lb反射。在坐位和仰卧位时均获得Ib抑制。这种抑制作用在站立和仰卧但负荷时显著减少或消失。在“简化”步态的站立阶段，8名受试者的抑制消失，甚至在6名受试者中观察到易化。可以得出结论，从腓肠肌到比目鱼肌的lb抑制减少发生在承重条件下，不需要运动。相比之下，lb易化需要运动，至少在一个基本的形式。(c)2006 Elsevier B. V.保留所有权利。
The role of force feedback during gait is still a matter of debate. From work on cats, it is known that input from Golgi tendon organs from triceps surae does produce lb facilitation during locomotion instead of autogenic inhibition. In humans, Stephens and Yang (Stephens, MJ., Yang, J.F., 1996. Short latency, non-reciprocal group I inhibition is reduced during the stance phase of walking in humans. Brain Res. 743, 24-31) found that voluntary contraction results in a reduction of Ib inhibition. During gait, they even observed lb facilitation in a subset of subjects. This raises the question whether the crucial elements involved in these changes are either loading of the leg or locomotion. To examine this question, lb reflexes were investigated during sitting, lying supine, lying supine with 300 N pressure applied to the foot sole, standing, and a rhythmic loading and unloading task called "reduced" gait. Ib inhibition was obtained during sitting and lying supine. This inhibition was significantly reduced or disappeared during standing and when lying supine but loaded. During the stance phase of "reduced" gait, the inhibition disappeared in eight subjects, and even a facilitation was observed in six subjects. It is concluded that the decrease in lb inhibition from gastrocnemius to soleus occurs during a load-bearing condition and does not require locomotion. In contrast, lb facilitation requires locomotion at least in a rudimentary form. (c) 2006 Elsevier B.V. All rights reserved.