New insights into helitron transposable elements in the mesopolyploid species Brassica rapa
New insights into helitron transposable elements in the mesopolyploid species Brassica rapa
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对中多倍体物种白菜中的 Helitron 转座元件的新见解
DOI：
10.1016/j.gene.2013.09.033
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发表时间：
2013-12-15
期刊：
影响因子：
3.5
通讯作者：
Hayward, Alice
中科院分区：
文献类型：
--
作者：
Fu, Donghui;Wei, Lijuan;Hayward, Alice
Helitrons是广泛存在于各种真核生物基因组中的DNA转座因子。Helitron与其他转座子的不同之处在于它们捕获基因片段的能力和它们的滚动复制机制。油菜是一种中多倍体植物，是世界上最重要的蔬菜和油料作物之一。在B中总共识别了787个helitron。将其划分为662个科和700个亚科。在helitron中发现了超过21，806个重复序列，其G+C含量与宿主helitron呈负相关。每个helitron平均包含2.9个基因片段和1.9个完整的基因，其中大部分被注释与代谢过程中的结合功能。此外，在174个helitrons中检测到一组114个非冗余microRNA，并预测调节一组787个非冗余靶基因。这些结果表明，helitrons有助于基因组结构和转录的变化，通过捕获基因片段和产生microRNA。(C)2013 Elsevier B.V.保留所有权利。
Helitrons are DNA transposable elements that are widely present in the genomes of diverse eukaryotic taxa. Helitrons are distinct from other transposons in their ability to capture gene fragments and their rolling-replication mechanism. Brassica rape is a mesopolyploid species and one of the most important vegetable and oil crops globally. A total of 787 helitrons were identified in the B. rapa genome and were assigned to 662 families and 700 subfamilies. More than 21,806 repetitive sequences were found within the helitrons, whose G+C content correlated negatively to that of the host helitron. Each helitron contained an average of 2.9 gene fragments and 1.9 intact genes, of which the majority were annotated with binding functions in metabolic processes. In addition, a set of 114 nonredundant microRNAs were detected within 174 helitrons and predicted to regulate a set of 787 nonredundant target genes. These results suggest that helitrons contribute to genomic structural and transcriptional variation by capturing gene fragments and generating microRNAs. (C) 2013 Elsevier B.V. All rights reserved.