A graph kernel based on context vectors for extracting drug-drug interactions
A graph kernel based on context vectors for extracting drug-drug interactions
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基于上下文向量的图内核,用于提取药物-药物相互作用
DOI:
10.1016/j.jbi.2016.03.014
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发表时间:
2016-06
影响因子:
4.5
通讯作者:
Jian Wang
中科院分区:
文献类型:
--
作者:
Wei Zheng;Hongfei Lin;Zhehuan Zhao;Bo Xu;Yijia Zhang;Zhihao Yang;Jian Wang
The clinical recognition of drug–drug interactions (DDIs) is a crucial issue for both patient safety and health care cost control. Thus there is an urgent need that DDIs be extracted automatically from biomedical literature by text-mining techniques. Although the top-ranking DDIs systems explore various features of texts, these features can’t yet adequately express long and complicated sentences. In this paper, we present an effective graph kernel which makes full use of different types of contexts to identify DDIs from biomedical literature. In our approach, the relations among long-range words, in addition to close-range words, are obtained by the graph representation of a parsed sentence. Context vectors of a vertex, an iterative vectorial representation of all labeled nodes adjacent and nonadjacent to it, adequately capture the direct and indirect substructures’ information. Furthermore, the graph kernel considering the distance between context vectors is used to detect DDIs. Experimental results on the DDIExtraction 2013 corpus show that our system achieves the best detection and classification performance (F-score) of DDIs (81.8 and 68.4, respectively). Especially for the Medline-2013 dataset, our system outperforms the top-ranking DDIs systems byF-scores of 10.7 and 12.2 in detection and classification, respectively.
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影响因子:
3
作者:
Kim S;Yoon J;Yang J;Park S
通讯作者:
Park S
DOI:
10.1142/9789814366496_0040
发表时间:
2011-12
影响因子:
--
作者:
B. Percha;Yael Garten;R. Altman
通讯作者:
B. Percha;Yael Garten;R. Altman
影响因子:
3
作者:
Airola, Antti;Pyysalo, Sampo;Bjoerne, Jari;Pahikkala, Tapio;Ginter, Filip;Salakoski, Tapio
通讯作者:
Salakoski, Tapio
DOI:
10.1007/978-3-319-10491-1_10
发表时间:
2014-09
期刊:
Procedia Computer Science
影响因子:
--
作者:
V. Ostuni;T. D. Noia;R. Mirizzi;E. Sciascio
通讯作者:
V. Ostuni;T. D. Noia;R. Mirizzi;E. Sciascio
DOI:
--
发表时间:
2013-06
期刊:
--
影响因子:
--
作者:
Isabel Segura-Bedmar;Paloma Martínez;María Herrero-Zazo
通讯作者:
Isabel Segura-Bedmar;Paloma Martínez;María Herrero-Zazo